探究对抗菌药物临床应用进行监测后，腹股沟疝修补术围手术期预防用药情况及手术切口感染发生情况。

选择2019年7月至2022年7月，庐江县中医院收治的389例腹股沟疝患者为研究对象，进行回顾性分析，根据抗菌药物应用方式分为A组与B组，A组为2019年7月—2020年12月，对抗菌药物临床应用进行监测前，常规应用抗菌药物的196例患者，B组为2021年1月—2022年7月，在药剂科临床药师监测和干预条件下应用抗菌药物的193例患者，均行经腹腹膜前腹股沟疝修补术治疗。统计2组围手术期预防性抗菌药物应用情况及手术切口感染发生情况。

2组患者的性别、年龄及手术部位等临床资料比较差异无统计学意义（P>0.05）；2组患者发热总发生率及切口愈合时间、术后住院时间比较差异均无统计学意义（P>0.05）；A组抗菌药物总使用率（61.22%）高于B组（18.13%），差异有统计学意义（P<0.05）；A、B组手术切口感染率分别为1.02%（2/196）、1.55%（3/193），差异无统计学意义（P>0.05）。

对抗菌药物临床应用进行监测后，腹股沟疝修补术围手术期抗菌药物的使用率明显降低，手术切口感染发生率及术后切口愈合情况无明显变化。

To explore the impact of clinical monitoring of antimicrobial drug use on perioperative prophylactic medication and the incidence of surgical site infections in inguinal hernia repair surgery.

A retrospective analysis was conducted on 389 patients with inguinal hernia treated at Lujiang Hospital of Traditional Chinese Medicine from July 2019 to July 2022. The patients were divided into two groups based on the method of antimicrobial drug use: Group A (196 patients from July 2019 to December 2020, before the monitoring of clinical use of antimicrobial drugs, routinely using antimicrobial drugs) and Group B (193 patients from January 2021 to July 2022, under the monitoring and intervention of clinical pharmacists in the pharmacy department, using antimicrobial drugs). All patients underwent transabdominal preperitoneal inguinal hernia repair surgery. The perioperative prophylactic use of antimicrobial drugs and the incidence of surgical site infections in both groups were statistically analyzed.

There were no significant differences in gender, age, or surgical site between the two groups (P>0.05). There were also no significant differences in the overall incidence of fever, wound healing time, or postoperative hospital stay between the two groups (P>0.05). The total use rate of antimicrobial drugs in Group A (61.22%) was higher than that in Group B (18.13%), with a statistical difference (P<0.05). The rates of surgical site infection in Groups A and B were 1.02% (2/196) and 1.55% (3/193), respectively, with no significant difference (P>0.05).

After the clinical monitoring of antimicrobial drugs, the use rate of antimicrobial drugs during the perioperative period of inguinal hernia repair surgery significantly decreased, while the incidence of surgical site infection and postoperative wound healing showed no significant change.