切换至 "中华医学电子期刊资源库"

中华疝和腹壁外科杂志(电子版) ›› 2024, Vol. 18 ›› Issue (06) : 693 -696. doi: 10.3877/cma.j.issn.1674-392X.2024.06.019

论著

腹壁疝术后感染的危险因素分析
杨闯1, 马雪1,()   
  1. 1.236300 安徽阜阳,阜南县人民医院检验科
  • 收稿日期:2024-03-29 出版日期:2024-12-18
  • 通信作者: 马雪

Analysis of risk factors for postoperative infection of abdominal wall hernia

Chuang Yang1, Xue Ma1,()   

  1. 1.Department of Clinical Laboratory, People's Hospital of Funan County, Fuyang 236300, Anhui Province, China
  • Received:2024-03-29 Published:2024-12-18
  • Corresponding author: Xue Ma
引用本文:

杨闯, 马雪. 腹壁疝术后感染的危险因素分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 693-696.

Chuang Yang, Xue Ma. Analysis of risk factors for postoperative infection of abdominal wall hernia[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(06): 693-696.

目的

探究腹壁疝术后感染的危险因素分析。

方法

回顾性分析2020 年1 月至2023年1 月阜南县人民医院296 例接受腹壁疝手术患者的临床资料,根据患者术后是否发生感染,将其分为感染组(36 例)和未感染组(260 例),采用单因素及Logistic 回归分析筛选腹壁疝术后感染的危险因素。

结果

共纳入腹壁疝手术患者296 例,其中发生术后感染患者36 例,术后感染的发生率为12.16%(36/296)。感染组和未感染组的性别、体重指数、高血压、饮酒、吸烟、手术时长、肠坏死、腹壁疝病史、腹部手术史,术后1 d 白蛋白、降钙素原(PCT)、中性粒细胞与淋巴细胞比值(NLR)比较,差异无统计学意义(P>0.05);而年龄、切口感染、糖尿病、肠坏死、二次手术、术后1 d C 反应蛋白(CRP)、白细胞计数等资料比较,差异有统计学意义(P<0.05);进行二元Logistic 回归分析,结果显示年龄≥65 岁(OR=3.224)、伤口感染(OR=3.517)、糖尿病(OR=3.187)、肠坏死(OR=4.046)、二次手术(OR=3.543)、术后1 d CRP(OR=3.701)、白细胞计数(OR=4.061)是发生腹壁疝术后感染的危险因素(P<0.05)。

结论

年龄、伤口感染、糖尿病、肠坏死、二次手术、术后1 d CRP、白细胞计数是腹壁疝术后感染的危险因素,根据其危险因素进行针对性的干预可有效降低腹壁疝术后感染。

Objective

To investigate the risk factors for postoperative infection in patients undergoing abdominal wall hernia surgery.

Methods

A retrospective analysis was conducted on the clinical data of 296 patients who underwent abdominal wall hernia surgery at Funan County People's Hospital from January 2020 to January 2023.Based on whether postoperative infection occurred, patients were divided into an infection group (36 cases) and a non-infection group (260 cases).Univariate analysis and logistic regression analysis were used to identify risk factors for postoperative infection.

Results

A total of 296 patients who underwent abdominal wall hernia surgery were included, with 36 patients experiencing postoperative infections, resulting in an infection rate of 12.16% (36/296).There were no statistically significant differences between the infection and non-infection groups in terms of sex, body mass index, hypertension, alcohol consumption, smoking, operation duration, bowel necrosis, history of abdominal wall hernia, history of abdominal surgery, postoperative day 1 albumin levels, procalcitonin(PCT), or the neutrophil-to-lymphocyte ratio (NLR) (P>0.05).However, significant differences were observed between the groups regarding age, wound infection, diabetes mellitus, bowel necrosis, reoperation,postoperative day 1 C-reactive protein (CRP), and white blood cell count (P<0.05).Binary logistic regression analysis identified age ≥65 years (OR=3.224), wound infection (OR=3.517), diabetes mellitus(OR=3.187), bowel necrosis (OR=4.046), reoperation (OR=3.543), postoperative day 1 CRP (OR=3.701),and white blood cell count (OR=4.061) as significant risk factors for postoperative infection (P<0.05).

Conclusion

Age, wound infection, diabetes mellitus, bowel necrosis, reoperation, postoperative day 1 CRP, and white blood cell count are risk factors for postoperative infection in patients undergoing abdominal wall hernia surgery.Targeted interventions based on these risk factors can effectively reduce the incidence of postoperative infections.

续表
项目 感染组(36例) 未感染组(260例) χ2 P
年龄[例(%)] 9.867 0.002
>65岁 23(63.89) 95(36.54)
≤65岁 13(36.11) 165(63.46)
性别[例(%)] 1.332 0.249
男性 25(69.44) 203(78.08)
女性 11(30.56) 57(21.92)
伤口感染[例(%)] 9.446 0.002
24(66.67) 103(39.62)
12(33.33) 157(60.38)
BMI[例(%)] 3.653 0.056
>25 kg/m2 20(55.56) 101(38.85)
≤25 kg/m2 16(44.44) 159(61.15)
糖尿病[例(%)] 9.438 0.002
22(61.11) 90(34.62)
14(38.89) 170(65.38)
高血压[例(%)] 1.442 0.230
10(27.78) 99(38.08)
26(72.22) 161(61.92)
饮酒[例(%)] 0.312 0.577
19(52.78) 150(57.69)
17(47.22) 110(42.31)
吸烟[例(%)] 0.540 0.463
20(55.56) 161(61.92)
16(44.44) 99(38.08)
手术时长[例(%)] 3.802 0.051
>2 h 21(58.33) 107(41.15)
≤2 h 15(41.67) 153(58.85)
肠坏死[例(%)] 10.032 0.002
24(66.67) 101(38.85)
12(33.33) 159(61.15)
二次手术[例(%)] 9.749 0.002
22(61.11) 89(34.23)
14(38.89) 171(65.77)
腹壁疝病史[例(%)] 0.338 0.561
9(25.00) 54(20.77)
27(75.00) 206(79.23)
腹部手术史[例(%)] 0.970 0.325
>3 d 11(30.56) 60(23.08)
≤3 d 25(69.44) 200(76.92)
术后1 d CRP[例(%)] 9.867 0.002
>11 mg/L 23(63.89) 95(36.54)
≤11 mg/L 13(36.11) 165(63.46)
白细胞计数[例(%)] 9.162 0.002
>20×109/L 24(66.67) 104(40.00)
≤20×109/L 12(33.33) 156(60.00)
术后1 d白蛋白(g/L,xˉ±s) 44.01±4.75 42.48±4.46 1.194 0.057
术后1 d PCT(ng/ml,xˉ±s) 1.25±0.41 1.128±0.39 1.863 0.063
术后1 d NLR(g/dl,xˉ±s) 8.44±2.06 7.95±1.52 1.729 0.085
表2 变量赋值
表3 Logistic 回归分析结果
[1]
陈璐, 张卓, 李鹏洲, 等.腹腔镜下腹壁疝腹膜外补片修补术与腹腔内补片修补术比较的多中心回顾性研究[J].中国普通外科杂志, 2023, 32(10): 1469-1475.
[2]
Peterman DE, Warren JA.Ventral hernia management in obese patients[J].Surg Clin North Am, 2021, 101(2): 307-321.
[3]
Köckerling F, Sheen AJ, Berrevoet F, et al.The reality of general surgery training and increased complexity of abdominal wall hernia surgery[J].Hernia, 2019, 23(6): 1081-1091.
[4]
Pavithira GJ, Dutta S, Sundaramurthi S, et al.Outcomes of emergency abdominal wall hernia repair: experience over a decade[J].Cureus, 2022, 14(6): e26324.
[5]
Shao JM, Deerenberg EB, Elhage SA, et al.Are laparoscopic and open ventral hernia repairs truly comparable?: a propensity-matched study in large ventral hernias[J].Surg Endosc, 2021, 35(8):4653-4660.
[6]
储招钱, 胡金灵, 童丽芳.腹股沟疝术后补片区感染危险因素及感染菌群的研究[J].浙江创伤外科, 2021, 26(6): 1114-1115.
[7]
中华医学会外科学分会疝和腹壁外科学组.腹壁切口疝诊疗指南(2012 年版)[J/OL].中华疝和腹壁外科杂志(电子版), 2013, 7(2):104-106.
[8]
Marcolin P, de Figueiredo SMP, Constante MM, et al.Drain placement in retromuscular ventral hernia repair: a systematic review and meta-analysis[J].Hernia, 2023, 27(3): 519-526.
[9]
余成建, 冯樱.腹股沟疝Lichtenstein 无张力修补术后慢性疼痛的影响因素分析及预测模型建立[J].局解手术学杂志, 2021, 30(8):713-718.
[10]
李凯, 王勇, 段鑫, 等.肥胖症对腹股沟疝术后手术部位感染的影响及处理[J].中华内分泌外科杂志, 2017, 11(3): 233-235.
[11]
张业骞, 董中毅, 张子臻, 等.结直肠癌预防性末端回肠造口部位切口疝临床特征及危险因素分析[J].中国实用外科杂志, 2022,42(11): 1265-1269, 1275.
[12]
蒙建源, 黄海, 朱刚健.不同术式对腹股沟疝的治疗效果、预后及疼痛的影响因素分析[J].临床外科杂志, 2023, 31(4): 368-371.
[13]
刘瞻, 赵英丽, 陈晓婷.维生素D 水平与2 型糖尿病并发肺部感染患者免疫功能及其预后的关系[J].中华医院感染学杂志, 2022,32(9): 1295-1298.
[14]
李家云, 方朝晖, 赵进东, 等.丹蛭降糖胶囊联合硫辛酸、依帕司他对气阴两虚夹瘀型糖尿病周围神经病变患者血糖水平和下肢神经功能的影响[J].现代生物医学进展, 2022, 22(15): 2898-2902.
[15]
Kohno S, Hasegawa T, Aoki H, et al.Analysis of risk factors for surgical site infection and postoperative recurrence following inguinal and femoral hernia surgery in adults[J].Asian J Surg, 2022,45(4): 1001-1006.
[16]
Chugh S, Pietropaolo A, Montanari E, et al.Predictors of urinary infections and urosepsis after ureteroscopy for stone disease: a systematic review from EAU Section of Urolithiasis(EULIS)[J].Curr Urol Rep, 2020, 21(4): 16.
[17]
Dai W, Chen Z, Zuo J, et al.Risk factors of postoperative complications after emergency repair of incarcerated groin hernia for adult patients: a retrospective cohort study[J].Hernia, 2019, 23(2): 267-276.
[18]
黄永刚, 叶静, 张方捷, 等.腹外斜肌转移肌瓣技术在巨大腹壁切口疝修补术中的应用价值[J].中华消化外科杂志, 2020, 19(7):757-761.
[19]
王苏, 武文杰, 毛淑平, 等.腹腔镜下腹股沟疝修补术后发生血清肿的影响因素分析[J].中国微创外科杂志, 2021, 21(11): 972-976.
[20]
黄玲玲, 赵晓飞, 辛晓阳, 等.PCT、CRP、SAA 和WBC 联合检测结合细菌培养对鲍曼不动杆菌感染的诊断价值[J].中国卫生检验杂志, 2022, 32(23): 2873-2878.
[21]
Oprea V, Buia F, Gheorghescu D, et al.Chronic mesh infection after incisional hernia repair.factors influencing negative outcomes of complete mesh removal[J].Chirurgia(Bucur), 2021, 116(3): 284-293.
[1] 明昊, 肖迎聪, 巨艳, 宋宏萍. 乳腺癌风险预测模型的研究现状[J/OL]. 中华乳腺病杂志(电子版), 2024, 18(05): 287-291.
[2] 庄燕, 戴林峰, 张海东, 陈秋华, 聂清芳. 脓毒症患者早期生存影响因素及Cox 风险预测模型构建[J/OL]. 中华危重症医学杂志(电子版), 2024, 17(05): 372-378.
[3] 黄鸿初, 黄美容, 温丽红. 血液系统恶性肿瘤患者化疗后粒细胞缺乏感染的危险因素和风险预测模型[J/OL]. 中华实验和临床感染病杂志(电子版), 2024, 18(05): 285-292.
[4] 罗文斌, 韩玮. 胰腺癌患者首次化疗后中重度骨髓抑制的相关危险因素分析及预测模型构建[J/OL]. 中华普通外科学文献(电子版), 2024, 18(05): 357-362.
[5] 梁孟杰, 朱欢欢, 王行舟, 江航, 艾世超, 孙锋, 宋鹏, 王萌, 刘颂, 夏雪峰, 杜峻峰, 傅双, 陆晓峰, 沈晓菲, 管文贤. 联合免疫治疗的胃癌转化治疗患者预后及术后并发症分析[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 619-623.
[6] 贺斌, 马晋峰. 胃癌脾门淋巴结转移危险因素[J/OL]. 中华普外科手术学杂志(电子版), 2024, 18(06): 694-699.
[7] 嵇振岭, 陈杰, 唐健雄. 重视复杂腹壁疝手术并发症的预防和处理[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 601-606.
[8] 江志鹏, 钟克力, 陈双. 复杂腹壁疝手术后腹腔高压与腹腔间室综合征的预防和处理[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 612-615.
[9] 王学虎, 赵渝. 复杂腹壁疝手术中血管损伤并发症的预防和处理[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 616-619.
[10] 林凯, 潘勇, 赵高平, 杨春. 造口还纳术后切口疝的危险因素分析与预防策略[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 634-638.
[11] 臧宇, 姚胜, 朱新勇, 戎世捧, 田智超. 低温等离子射频消融治疗腹壁疝术后补片感染的临床效果[J/OL]. 中华疝和腹壁外科杂志(电子版), 2024, 18(06): 687-692.
[12] 张伟伟, 陈启, 翁和语, 黄亮. 随机森林模型预测T1 期结直肠癌淋巴结转移的初步研究[J/OL]. 中华结直肠疾病电子杂志, 2024, 13(05): 389-393.
[13] 司楠, 孙洪涛. 创伤性脑损伤后肾功能障碍危险因素的研究进展[J/OL]. 中华脑科疾病与康复杂志(电子版), 2024, 14(05): 300-305.
[14] 颜世锐, 熊辉. 感染性心内膜炎合并急性肾损伤患者的危险因素探索及死亡风险预测[J/OL]. 中华临床医师杂志(电子版), 2024, 18(07): 618-624.
[15] 李文哲, 王毅, 崔建, 郑启航, 王靖彦, 于湘友. 新疆维吾尔自治区重症患者急性肾功能异常的危险因素分析[J/OL]. 中华卫生应急电子杂志, 2024, 10(05): 269-276.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?