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中华疝和腹壁外科杂志(电子版) ›› 2019, Vol. 13 ›› Issue (02) : 169 -173. doi: 10.3877/cma.j.issn.1674-392X.2019.02.018

所属专题: 文献

循证医学

腹股沟疝修补术后放置引流与否对血清肿形成的影响的Meta分析
郭晓1, 王辰2, 崔逸峰1, 宋瑞鹏1, 陆朝阳1,()   
  1. 1. 150001 哈尔滨医科大学附属第一医院肝脏外科
    2. 150046 哈尔滨,中国人民解放军93220部队卫生队
  • 收稿日期:2018-05-24 出版日期:2019-04-18
  • 通信作者: 陆朝阳
  • 基金资助:
    吴阶平医学基金(320.6750.16206)

Meta-analysis of the effect of drainage after inguinal hernia repair on seroma formation

Xiao Guo1, Chen Wang2, Yifeng Cui1, Ruipeng Song1, Zhaoyang Lu1,,()   

  1. 1. Department of Liver Surgery, First Affiliated Hospital of Harbin Medical University, Harbin 150001, China
    2. Chinese People's Liberation Army 93220 Force Health Team, Harbin 150046, China
  • Received:2018-05-24 Published:2019-04-18
  • Corresponding author: Zhaoyang Lu
  • About author:
    Corresponding author: Lu Zhaoyang, Email:
引用本文:

郭晓, 王辰, 崔逸峰, 宋瑞鹏, 陆朝阳. 腹股沟疝修补术后放置引流与否对血清肿形成的影响的Meta分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2019, 13(02): 169-173.

Xiao Guo, Chen Wang, Yifeng Cui, Ruipeng Song, Zhaoyang Lu. Meta-analysis of the effect of drainage after inguinal hernia repair on seroma formation[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2019, 13(02): 169-173.

目的

分析比较腹股沟疝修补术后放置引流与不放置引流对预防血清肿形成的疗效。

方法

检索PubMed、web of science、science direct、ovid和CNKI数据库,检索时限均为从建库至至2016年10月,选择腹股沟疝修补术后放置引流与不放置引流的临床对照研究,2位作者分别独立进行文献筛选、资料提取及质量评估,使用Cochrane 5.0.1系统评价手册进行Meta分析。

结果

共纳入2项随机对照临床研究和4项回顾性临床对照研究,包括3 448例患者,其中术后放置引流组2 607例,术后未放置引流组841例。对纳入研究进行整体分析显示,放置引流组总体在减少术后血清中发生率方面高于未放置引流组(P=0.007),相对危险度为0.29,95%可信区间(CI):0.12~0.72;放置引流组总体在增加手术时间方面高于未放置组(P=0.006),标准化均数差为0.36,95% CI:0.22~0.51。2组总体在住院时间比较,差异无统计学意义(P>0.05)。

结论

腹股沟疝术后放置引流可以减少术后严重血清肿的形成,因此是安全可行的。

Objective

To analyze the effect of drainage and non-drainage after inguinal hernia repair on the prevention of seroma formation.

Methods

PubMed, web of science, science direct, ovid and CNKI databases were searched and submitted for search until October 2016. A controlled clinical study comparing drainage and non-drainage after inguinal herniorrhaphy was performed. The authors independently performed literature screenings. Data extraction and quality assessment were performed using the Cochrane 5.0.1 systematic review manual for meta-analysis.

Results

A total of 2 randomized controlled clinical studies and 4 retrospective clinical controlled studies were included, including 3 448 patients, of whom 2 607 were placed drainage after surgery and 841 without drainage. The overall analysis of the included studies showed that compared with the non-drainage group, the drainage group had a higher overall incidence in the reduction of postoperative seroma than the non-drainage group (P=0.007), relative risk was 0.29 (95% CI: 0.12-0.72); the overall increased operative time in drainage group was higher than that in non-drainage group (P=0.006), the STD Mean Difference was 0.36 (95% CI: 0.22-0.51). There was no significant difference in the length of hospital stay between the two groups.

Conclusion

Drainage after inguinal hernia surgery can reduce the formation of seroma, so it is safe and feasible.

图1 PRISMA文献检索流程图
表1 纳入文献的基本特征
表2 纳入文献的偏倚风险评价
图2 血清肿发生率的文献漏斗图
图3 2组术后血清肿的森林图
图4 2组手术时间的森林图
图5 2组住院时间的森林图
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