Treatment effect of butorphanol and sufentanil on chills in patients undergoing unilateral hernia repair with combined spinal-epidural anesthesia

doi:10.3877/cma.j.issn.1674-392X.2022.01.017

Abstract

Abstract:

Objective

To analyze the effects of butorphanol and sufentanil on the treatment of chills in patients undergoing unilateral hernia repair with combined spinal-epidural anesthesia.

Methods

A total of 300 patients underwent unilateral hernia repair with combined spinal-epidural anesthesia in Chongqing Banan District People's Hospital from January 2019 to January 2021 were selected as the research subjects. According to different anesthesia methods, the patients were divided into group A and group B. 150 patients in group A received intravenous butorphanol, and 150 patients in group B received sufentanil intravenous injection. The treatment effects on chills were compared between the two groups. The hemodynamics before medication, 1, 5, 10 minutes after medication and after operation were compared. Visual analogue scale (VAS) and Ramsay sedation score (RSS) before operation (T0), 4 hours (T1), 12 hours (T2), 24 hours (T3) and 48 hours (T4) after operation were compared.

Results

The total effective rate on chills in group A (96.00%) was significantly higher than that in group B (90.00%), and the difference was statistically significant (P<0.05). From 1 minutes after treatment to the end of the operation, the MAP, SpO₂ and HR have varying degrees of fluctuations compared with those before medication (P<0.05), but the differences between two groups were not statistically significant (P>0.05). At T1 to T4, the VAS score of group B was significantly lower than that of group A compared with time T0 (P<0.05), the RSS score of group B was significantly higher than that of group A (P<0.05).

Conclusion

Butorphanol can reduce the incidence of chills in patients undergoing unilateral hernia repair with combined spinal-epidural anesthesia, while sufentanil can exert a strong analgesic and sedative effect with a better effect.

Key words: Butorphanol, Sufentanil, Combined spinal-epidural anesthesia, Hernia

Tuoyu Li, Chunhong Liu. Treatment effect of butorphanol and sufentanil on chills in patients undergoing unilateral hernia repair with combined spinal-epidural anesthesia[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2022, 16(01): 74-77.

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References 17

[1]	秦树国，赵明，周颖. 全身麻醉和腰硬联合麻醉对老年全髋关节置换术术后麻醉恢复期的影响[J]. 中国老年学杂志, 2016, 36(6): 1395-1397.
[2]	安仙泉，方美丹，王聪, 等. 右美托咪定与咪达唑仑复合腰硬联合麻醉对老年髋关节置换术患者早期认知功能和炎症因子的影响[J]. 中国老年学, 2017, 37(2): 428-429.
[3]	张鑫，吴秀英. 曲马多、酒石酸布托啡诺与盐酸右美托咪定治疗腰硬联合麻醉剖宫产患者寒战的效果比较[J]. 实用药物与临床, 2015, 18(3): 284-288.
[4]	张莉，刘宗英，王文明. 酒石酸布托啡诺联合地塞米松治疗腰硬联合麻醉寒战的临床观察[J]. 四川医学, 2015, 36(3): 392-394, 395.
[5]	陈颖洁，黄绍强. 布托啡诺与舒芬太尼镇痛效应的相互作用[J]. 中华麻醉学杂志, 2017, 37(8): 975-978.
[6]	中华医学会外科学分会疝和腹壁外科学组. 中国疝和腹壁外科诊疗指南(2012年版)[J]. 临床外科杂志, 2013, 21(6): 405-407.
[7]	Wrench IJ, Singh P, Dennis AR, et al. The minimum effectie dose ofpethidine and doxapram in the treatment of post-anaesthetic shivering[J]. Anaesthsia, 1997, 52(1): 32-36．
[8]	陶萍. 应用VAS评分对骨折术后患者实施疼痛干预的护理[J]. 中国伤残医学, 2015, 23(20): 135-136.
[9]	周越，李明凤，黄文霞, 等. 镇静评估量表的研究进展[J]. 护理研究, 2013, 27(5): 1161-1164.
[10]	阮志华，郑晓明. 腰硬联合麻醉在剖宫产手术中的应用价值研究[J]. 世界中医药, 2015, 10(A2): 1068-1069.
[11]	崔哲. 使用地佐辛与曲马多治疗腰硬联合麻醉剖宫产术中寒战的效果比较[J]. 世界中医药, 2016, 11(B3): 1060-1061.
[12]	王跃军. 布托啡诺预防腰硬联合麻醉下阑尾切除术寒战反应的效果研究[J]. 现代中西医结合杂志, 2016, 25(26): 2951-2953.
[13]	王连建. 小儿腹腔镜疝气手术中舒芬太尼联合七氟醚麻醉的有效性及安全性分析[J]. 中国民间疗法, 2020, 28(9): 96-98.
[14]	徐茜，李有长，胡佳. 小剂量舒芬太尼在剖宫产术腰硬联合麻醉中预防寒战及牵拉痛的临床观察[J]. 中国医药导报, 2016, 13(4): 85-88.
[15]	廉海云，刘国利. 右美托咪定联合布托啡诺在老年患者经尿道前列腺电切术中的应用[J]. 广东医学, 2020, 41(6): 634-637.
[16]	钟超超，刘功俭. 舒芬太尼与酒石酸布托啡诺在急诊与择期剖宫产患者的镇痛效果比较[J]. 山东医药, 2015, 55(37): 84-85.
[17]	郭浩，李志山，王治, 等. 右美托咪定复合舒芬太尼应用于经皮椎间孔镜手术的临床效果[J]. 中国医药, 2019, 14(7): 1054-1057.

组别	例数	消失	减轻	无效	总有效率
A组	150	112(74.67)	32(21.33)	6(4.00)	144(96.00)
B组	150	96(64.00)	39(26.00)	15(10.00)	135(90.00)^a

组别	例数	消失	减轻	无效	总有效率
A组	150	112(74.67)	32(21.33)	6(4.00)	144(96.00)
B组	150	96(64.00)	39(26.00)	15(10.00)	135(90.00)^a

组别	例数	用药前	用药后1 min	用药后5 min	用药后10 min	术毕
A组	150	88.05±4.91	90.23±5.17^a	92.23±5.22^a	95.97±5.05^a	94.97±5.39^a
B组	150	88.223±4.96	90.35±5.26^a	92.01±5.41^a	95.83±5.11^a	94.76±5.43^a
t值		0.298	0.199	0.358	0.239	0.336
P值		>0.05	>0.05	>0.05	>0.05	>0.05

组别	例数	用药前	用药后1 min	用药后5 min	用药后10 min	术毕
A组	150	88.05±4.91	90.23±5.17^a	92.23±5.22^a	95.97±5.05^a	94.97±5.39^a
B组	150	88.223±4.96	90.35±5.26^a	92.01±5.41^a	95.83±5.11^a	94.76±5.43^a
t值		0.298	0.199	0.358	0.239	0.336
P值		>0.05	>0.05	>0.05	>0.05	>0.05

组别	例数	用药前	用药后1 min	用药后5 min	用药后10 min	术毕
A组	150	97.78±3.16	98.91±3.54^a	99.12±3.67^a	99.36±3.74^a	98.52±3.57^a
B组	150	97.82±3.19	98.87±3.61^a	99.25±3.71^a	99.41±3.79^a	98.69±3.54^a
t值		0.109	0.097	0.305	0.115	0.414
P值		>0.05	>0.05	>0.05	>0.05	>0.05

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