切换至 "中华医学电子期刊资源库"

中华疝和腹壁外科杂志(电子版) ›› 2026, Vol. 20 ›› Issue (01) : 10 -14. doi: 10.3877/cma.j.issn.1674-392X.2026.01.002

专家论坛

疝修补材料的发展趋势:从力学覆盖到功能修复
曹桢, 张起尧, 刘子文()   
  1. 100730 中国医学科学院 北京协和医学院 北京协和医院基本外科
  • 收稿日期:2026-01-04 出版日期:2026-02-18
  • 通信作者: 刘子文
  • 基金资助:
    国家自然科学基金面上项目(81572459,82172727); 北京市自然科学基金面上项目(7202164)

Emerging trends in hernia repair materials: from mechanical reinforcement to functional restoration

Zhen Cao, Qiyao Zhang, Ziwen Liu()   

  1. Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2026-01-04 Published:2026-02-18
  • Corresponding author: Ziwen Liu
引用本文:

曹桢, 张起尧, 刘子文. 疝修补材料的发展趋势:从力学覆盖到功能修复[J/OL]. 中华疝和腹壁外科杂志(电子版), 2026, 20(01): 10-14.

Zhen Cao, Qiyao Zhang, Ziwen Liu. Emerging trends in hernia repair materials: from mechanical reinforcement to functional restoration[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2026, 20(01): 10-14.

疝是普通外科的常见疾病,手术修补仍是目前唯一的治愈方式。为恢复腹壁结构的完整性与功能稳定,疝修补术通常需植入补片进行重建。随着材料学及工程技术的不断发展,疝修补材料在种类和结构上日益丰富,其力学性能、生物相容性及临床适应证等方面存在明显差异,但理想修补材料仍有待进一步探索。日间疝手术模式的推广,对疝修补材料提出了更高的要求。本文系统回顾疝修补材料的发展历程与研究现状,重点介绍目前常用补片类型及其临床应用特点,并结合近年来材料设计的新趋势,对其未来发展方向进行分析,以期为疝修补材料的合理选择及相关研究提供参考。

Hernia is a common disease in general surgery, and surgical repair remains the only curative treatment at present. To restore the structural integrity and functional stability of the abdominal wall, hernia repair procedures usually require the implantation of mesh for reconstruction. With the continuous development of materials science and engineering technology, hernia repair materials have become increasingly diverse in type and structure, exhibiting notable differences in mechanical properties, biocompatibility, and clinical indications; however, the ideal repair material remains to be further explored. The promotion of the ambulatoryhernia surgery model has imposed higher requirements on hernia repair materials. This article systematically reviews the development history and current research status of hernia repair materials, with a focus on commonly used mesh types and their clinical application characteristics. In addition, in light of recent trends in material design, the future development directions are analyzed, with the aim of providing a reference for the rational selection of hernia repair materials and for related research.

[1]
中华医学会外科学分会疝与腹壁外科学组, 中国医师协会外科医师分会疝和腹壁外科专家工作组. 腹股沟疝诊疗指南(2024版)[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(1): 1-8.
[2]
Saiding Q, Chen Y, Wang J, et al. Abdominal wall hernia repair: from prosthetic meshes to smart materials[J]. Mater Today Bio, 2023, 29(21): 100691.
[3]
Bringman S, Conze J, Cuccurullo D, et al. Hernia repair: the search for ideal meshes[J]. Hernia, 2010, 14(1): 81-87.
[4]
Patsouris S, Mallis P, Michalopoulos E, et al. Advances in Innovative Surgical Implant Manufacturing for Hernia Repair and Soft Tissue Reconstruction[J]. Bioengineering(Basel), 2025, 12(11): 1182.
[5]
中国日间手术合作联盟, 《中华疝和腹壁外科杂志(电子版)》编委会, 中国医师协会外科医师分会疝和腹壁外科学组, 等. 中小腹壁疝日间手术规范化流程中国专家共识(2022版)[J]. 中华消化外科杂志, 2022, 21(9): 1165-1172.
[6]
唐健雄, 朱雷, 李绍杰. 疝与腹壁外科现状与修补材料创新研究发展[J]. 中华消化外科杂志, 2018, 17(11): 1071-1075.
[7]
刘德琦, 刘姗, 袁浩然, 等. 疝补片材料研究进展[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(5): 582-588.
[8]
Lichtenstein IL, Shulman AG, Amid PK, et al. The tension-free hernioplasty[J]. Am J Surg, 1989, 157(2): 188-193.
[9]
李绍春, 顾岩, 胡星辰, 等. 不同聚丙烯补片在成人腹股沟疝修补术中的应用价值[J]. 中华消化外科杂志, 2020, 19(7): 767-772.
[10]
Dogu D, Akyol O, Sokmensuer C, et al. Platelet-rich fibrin decreases adhesion to polypropylene prosthetic mesh material in ventral hernia repair[J]. Sci Rep, 2025, 15(1): 17902.
[11]
Dufay M, Jimenez M, Casetta M, et al. Abdominal PP meshes coated with functional core-sheath biodegradable nanofibers with anticoagulant and antibacterial properties[J]. Biomater Adv, 2025, 169: 214163.
[12]
Zhang X, Hu K, Xue J, et al. Experimental methodology used for testing in vivo adhesion of composite meshes for incisional hernia repair: a scoping review[J]. RSC Adv, 2025, 15(43): 36319-36330.
[13]
赵思琦, 孟岩, 孙中伟. 复合补片与生物补片在腹腔镜脐疝修补术中疗效对比研究[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(5): 535-538.
[14]
靳翠红, 郑若彤, 邵怀军, 等. 可吸收补片在腹腔镜腹壁疝修补术中的应用进展[J]. 中华消化外科杂志, 2025, 24(9): 1148-1152.
[15]
Xu W, Yagoshi K, Koga Y, et al. Optimized polymer coating for magnesium alloy-based bioresorbable scaffolds for long-lasting drug release and corrosion resistance[J]. Colloids Surf B Biointerfaces, 2018, 163: 100-106.
[16]
孙立, 陈杰, 申英末, 等. 生物补片在腹股沟疝治疗中应用[J]. 中国实用外科杂志, 2017, 37(11): 1223-1227.
[17]
常帅, 张迪, 赵耀, 等. 生物补片与合成补片在腹腔镜腹股沟疝修补术中的应用价值[J]. 中国内镜杂志, 2025, 31(6): 39-43.
[18]
郑若彤, 赵敏娴, 狄治杉, 等. 生物可降解补片在腹壁疝修补术中的临床应用进展[J]. 临床外科杂志, 2024, 32(9): 904-907.
[19]
Wiley AJ, Jensen SM, Holland AM, et al. Open, complex abdominal wall reconstruction with synthetic versus biologic mesh: Outcomes with a minimum of 5-year follow-up[J]. Surgery, 2025, 11: 109961.
[20]
Guan L, Nie Y, Liu X, et al. Prospective cohort study of biological versus and synthetic meshes for laparoscopic repair of hiatal hernia[J]. Hernia, 2025, 30(1): 20.
[21]
Carvalho AC, Santos FAV, De Carvalho Garcia DP. Meta-analysis of controlled studies comparing biologic and synthetic unabsorbable mesh in contaminated fields[J]. Surg Endosc, 2025, 39(7): 4094-4101.
[22]
Seefeldt CS, Knievel J, Deeb M, et al. Biological vs Synthetic Mesh in Laparoendoscopic Inguinal Hernia Repair: The BIOLAP Randomized Clinical Trial[J]. JAMA Surg, 2025, 160(12): 1309-1316.
[23]
Huang H, Tang F, Gan W, et al. GelMA/tannic acid hydrogel decorated polypropylene mesh facilitating regeneration of abdominal wall defects[J]. Biomater Sci, 2024, 12(24): 6392-6402.
[24]
Wang X, Liu C, Li X, et al. A novel electrospun polylactic acid silkworm fibroin mesh for abdominal wall hernia repair[J]. Mater Today Bio, 2023, 15(24): 100915.
[25]
Liu L, Liu J, Weng C, et al. Matrix-bound nanovesicles drive the engineering of immunomodulatory meshes for abdominal hernia repair[J]. Biomater Adv, 2026, 180: 214587.
[26]
Olmos-Juste R, Olza S, Gabilondo N, et al. Tailor-Made 3D Printed Meshes of Alginate-Waterborne Polyurethane as Suitable Implants for Hernia Repair[J]. Macromol Biosci, 2022, 22(9): e2200124.
[27]
Calero Castro FJ, Yuste Y, Pereira S, et al. Proof of concept, design, and manufacture via 3-D printing of a mesh with bactericidal capacity: Behaviour in vitro and in vivo[J]. J Tissue Eng Regen Med, 2019, 13(11): 1955-1964.
[28]
Ballard DH, Jammalamadaka U, Tappa K, et al. 3D printing of surgical hernia meshes impregnated with contrast agents: in vitro proof of concept with imaging characteristics on computed tomography[J]. 3D Print Med, 2018, 4(1): 13.
[29]
Young E, Lawson J, Karatassas A, et al. To infinity and beyond: the promise of data-driven 3D printing of hernia mesh-a primer for surgeons[J]. Hernia, 2025, 29(1): 270.
[30]
邓先锐, 郑磊, 徐通海, 等. 日间手术模式在腹股沟疝修补术中的应用价值[J]. 中华消化外科杂志, 2023, 22(9): 1075-1079.
[31]
《中华疝和腹壁外科杂志(电子版)》编辑委员会, 全国卫生产业企业管理协会疝和腹壁外科产业及临床研究分会, 中国医师协会外科医师分会疝和腹壁外科专家工作组, 等. 成人腹股沟疝日间手术管理模式下加速康复策略专家共识[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(2): 125-131.
[32]
申英末, 孙立, 陈杰. 腹股沟疝日间手术的发展历程及诊疗经验[J]. 中华消化外科杂志, 2020, 19(7): 725-728.
[1] 潘子杭, 杨丽华, 孙轶群, 丁美军, 薛珂. 表皮干细胞来源外泌体在创面修复中应用的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(01): 58-62.
[2] 廖睿, 查天建, 刘小龙. RNA结合蛋白在糖尿病足溃疡中作用的研究进展[J/OL]. 中华损伤与修复杂志(电子版), 2026, 21(01): 75-79.
[3] 张新春, 王昕, 范乐. 功能、美学和微创导向的数字化咬合重建:临床路径与关键技术[J/OL]. 中华口腔医学研究杂志(电子版), 2026, 20(01): 34-39.
[4] 文晋, 丁文婧, 朱梓园. 贴面修复治疗中"美学与功能兼顾"理念的临床实践调查[J/OL]. 中华口腔医学研究杂志(电子版), 2026, 20(01): 61-68.
[5] 张鑫, 余朝文, 王孝高, 李金泽, 陈世远. 颈动脉长段病变行颈动脉内膜剥脱生物补片成形术[J/OL]. 中华普通外科学文献(电子版), 2025, 19(06): 382-382.
[6] 魏平, 赵鑫, 田广健. 腹腔镜下置入IPST专用疝补片并开放原位造口重建治疗造口旁疝疗效分析(附52例报告)[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(01): 67-70.
[7] 朱江帆, 杜磊, 王玥, 贾许杨, 卢列盛. 胃袖状切除后胃食管移位的修正手术:下段食管复位、食管裂孔修补及四点固定[J/OL]. 中华普外科手术学杂志(电子版), 2026, 20(01): 13-13.
[8] 中国日间手术合作联盟疝和腹壁外科专业日间手术专家委员会, 《中华疝和腹壁外科杂志(电子版)》编辑委员会, 全国卫生产业企业管理协会疝和腹壁外科产业及临床研究分会, 中国医师协会外科医师分会疝和腹壁外科专家工作组, 中华医学会外科学分会疝与腹壁外科学组, 中华消化外科菁英荟疝与腹壁外科学组, 中华志愿者协会中西医结合专家工作委员会疝和腹壁外科全国专业组, 中国非公立医疗机构协会日间手术与疝外科专业委员会. 腹股沟疝日间手术规范化流程与标准专家指南(2026版)[J/OL]. 中华疝和腹壁外科杂志(电子版), 2026, 20(01): 1-9.
[9] 钟秋润, 严丹檎, 范小莉, 陈蓉, 罗坤. 腹股沟疝修补术后发生血清肿危险因素的Meta分析[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(06): 701-706.
[10] 刘沐阳, 沈晓军, 史立洲, 谭华志, 王睿杰, 程杰, 吴凡, 顾隆淼. 术后血清肿:腹股沟疝修补术的潜在挑战及干预策略[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(06): 712-716.
[11] 王佳杰, 李文波. 3D腹腔镜在腹股沟疝治疗中的临床应用进展[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(06): 717-721.
[12] 朱少伟. 未合并隐睾的小儿半月线疝一例并文献复习[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(06): 722-724.
[13] 吴茜, 杨董超, 董文培, 宋致成, 顾岩. 从宏观支撑到微观调控:重视力学微环境在疝修补材料设计中的应用[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(06): 633-637.
[14] 吴鹏飞, 官昕禹, 纳孜也尔克·吾拉尔别克, 阿丽耶·麦麦提伊敏, 努佳丽克·克德汉, 陈奕辰, 帕孜力亚·艾克热木, 马泽坤. 自体嗅鞘细胞在视神经损伤修复中的潜在机制与应用[J/OL]. 中华神经创伤外科电子杂志, 2025, 11(06): 371-375.
[15] 高怀军, 余伟. 嵌顿性腹股沟疝患者急诊腹腔镜术后预后不良的危险因素分析[J/OL]. 中华卫生应急电子杂志, 2025, 11(06): 356-360.
阅读次数
全文


摘要


AI


AI小编
你好!我是《中华医学电子期刊资源库》AI小编,有什么可以帮您的吗?