Comparison of Desarda and Lichtenstein in inguinal hernia repair: a meta-analysis

doi:10.3877/cma.j.issn.1674-392X.2023.03.005

Abstract

Abstract:

Objective

To compare the efficacy and safety of Desarda and Lichtenstein in inguinal hernia repair.

Methods

Two researchers searched the electronic medical database (PubMed, EMBASE, Cochrane Library, Wanfang, China National Knowledge Infrastructure, and VIP Chinese Science and Technology Journal Database) for randomized controlled trials comparing Desarda surgery with Lichtenstein surgery for the treatment of inguinal hernias from January 2000 to September 2020. The quality of the studies was assessed, and the pertinent data were collected. Recurrence rate and total postoperative complications were the primary outcome indicators. Surgical site infection (SSI), chronic groin discomfort or numbness, seroma or hematoma, operation time, early postoperative pain score, total time to return to regular daily activities or a job, and testicular atrophy were secondary outcome measures. Data from the included literature was gathered and subjected to a meta-analysis for analysis.

Results

A total of 10 RCTs involving 3211 patients were included, including 1573 in the Desarda group and 1638 in the Lichtenstein group. There were significant differences between the Desarda group and the Lichtenstein group in postoperative complications, surgical site infection (SSI), chronic groin pain or numbness, seroma or hematoma formation, and operation time. There was no significant difference in recurrence rate, early postoperative pain, the total time to return to normal daily activities or work, and testicular atrophy.

Conclusion

Desarda is superior to Lichtenstein in reducing postoperative complications, especially SSI, chronic inguinal pain or numbness, hematoma, or seroma.

Key words: Hernia, inguinal, Herniorrhaphy, Meta-analysis, Lichtenstein, Desarda

Xiangyuan Ding, Xiaoying Ren, Huiming Yan. Comparison of Desarda and Lichtenstein in inguinal hernia repair: a meta-analysis[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2023, 17(03): 255-263.

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Figures/Tables 14

References 38

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第一作者	发表年份	国家	研究持续时间	随访时间(月)	人口分布
第一作者	发表年份	国家	研究持续时间	随访时间(月)	DT	LT
Ahmed^[8]	2018	埃及	2012-05至2016-11	36	65/130	65/130
Arafa^[9]	2020	埃及	2016-03至2019-03	24	40/80	40/80
Muhammad^[10]	2017	巴基斯坦	2017-01至2017-06	6	30/60	30/60
Poongavanam^[11]	2018	印度	2017至2018	12	51/102	51/102
Rahman^[12]	2019	孟加拉国	2013-10至2016-10	24	54/100	46/100
Rodriguez^[13]	2018	古巴	2002-01至2016-12	120	1075/2225	1150/2225
Sowmya^[14]	2015	印度	2006-06至2008-05	12	20/40	20/40
Szopinski^[15]	2012	波兰	2005-01至2006-06	36	105/208	103/208
Vupputuri^[16]	2019	印度	2013-08至2013-10	36	62/123	61/123
Youssef^[17]	2015	埃及	2010-12至2012-12	24	71/143	72/143

第一作者	发表年份	国家	研究持续时间	随访时间(月)	人口分布
第一作者	发表年份	国家	研究持续时间	随访时间(月)	DT	LT
Ahmed^[8]	2018	埃及	2012-05至2016-11	36	65/130	65/130
Arafa^[9]	2020	埃及	2016-03至2019-03	24	40/80	40/80
Muhammad^[10]	2017	巴基斯坦	2017-01至2017-06	6	30/60	30/60
Poongavanam^[11]	2018	印度	2017至2018	12	51/102	51/102
Rahman^[12]	2019	孟加拉国	2013-10至2016-10	24	54/100	46/100
Rodriguez^[13]	2018	古巴	2002-01至2016-12	120	1075/2225	1150/2225
Sowmya^[14]	2015	印度	2006-06至2008-05	12	20/40	20/40
Szopinski^[15]	2012	波兰	2005-01至2006-06	36	105/208	103/208
Vupputuri^[16]	2019	印度	2013-08至2013-10	36	62/123	61/123
Youssef^[17]	2015	埃及	2010-12至2012-12	24	71/143	72/143

第一作者	组别	病例数	年龄(岁,±s)	性别(例,男:女)	疝的位置（例）			结局指标
第一作者	组别	病例数	年龄(岁,±s)	性别(例,男:女)	右侧	左侧	双侧	结局指标
Ahmed^[8]	DT	65	38±11.55	61:4	39	21	5	A B
Ahmed^[8]	LT	65	40±11.69	65:0	41	18	6	A B
Arafa^[9]	DT	40	32.8±7.9	不详	8	32	不详	A B C D E F G H I
Arafa^[9]	LT	40	34.65±8.12	不详	13	27	不详	A B C D E F G H I
Muhammad^[10]	DT	30	50.24±10.89	30:0	不详	不详	不详	A B C E F G
Muhammad^[10]	LT	30	52.13±12.55	30:0	不详	不详	不详	A B C E F G
Poongavanam^[11]	DT	51	不详	不详	33	18	0	A B E F
Poongavanam^[11]	LT	51	不详	不详	31	20	0	A B E F
Rahman^[12]	DT	54	50.33±5.12	54:0	35	19	0	A B C D E F G H
Rahman^[12]	LT	46	56.17±6.34	46:0	30	16	0	A B C D E F G H
Rodriguez^[13]	DT	1075	58.2	1002:73	530	510	35	A B D E I
Rodriguez^[13]	LT	1150	57.4	1077:73	552	522	76	A B D E I
Sowmya^[14]	DT	20	46.6±16.2	20:0	15	5	0	A B D E H
Sowmya^[14]	LT	20	44.1±12.9	20:0	14	6	0	A B D E H
Szopinski^[15]	DT	105	50.2±17.5	105:0	59	42	4	A B C E I
Szopinski^[15]	LT	103	54.1±15.3	103:0	54	41	8	A B C E I
Vupputuri^[16]	DT	62	49.97±13.25	62:0	不详	不详	不详	A B C D E F G
Vupputuri^[16]	LT	61	53.13±11.31	61:0	不详	不详	不详	A B C D E F G
Youssef^[17]	DT	71	45.97±10.69	69:2	49	22	0	A B C D E F G H
Youssef^[17]	LT	72	43.89±10.27	69:3	56	16	0	A B C D E F G H

第一作者	组别	病例数	年龄(岁,±s)	性别(例,男:女)	疝的位置（例）			结局指标
第一作者	组别	病例数	年龄(岁,±s)	性别(例,男:女)	右侧	左侧	双侧	结局指标
Ahmed^[8]	DT	65	38±11.55	61:4	39	21	5	A B
Ahmed^[8]	LT	65	40±11.69	65:0	41	18	6	A B
Arafa^[9]	DT	40	32.8±7.9	不详	8	32	不详	A B C D E F G H I
Arafa^[9]	LT	40	34.65±8.12	不详	13	27	不详	A B C D E F G H I
Muhammad^[10]	DT	30	50.24±10.89	30:0	不详	不详	不详	A B C E F G
Muhammad^[10]	LT	30	52.13±12.55	30:0	不详	不详	不详	A B C E F G
Poongavanam^[11]	DT	51	不详	不详	33	18	0	A B E F
Poongavanam^[11]	LT	51	不详	不详	31	20	0	A B E F
Rahman^[12]	DT	54	50.33±5.12	54:0	35	19	0	A B C D E F G H
Rahman^[12]	LT	46	56.17±6.34	46:0	30	16	0	A B C D E F G H
Rodriguez^[13]	DT	1075	58.2	1002:73	530	510	35	A B D E I
Rodriguez^[13]	LT	1150	57.4	1077:73	552	522	76	A B D E I
Sowmya^[14]	DT	20	46.6±16.2	20:0	15	5	0	A B D E H
Sowmya^[14]	LT	20	44.1±12.9	20:0	14	6	0	A B D E H
Szopinski^[15]	DT	105	50.2±17.5	105:0	59	42	4	A B C E I
Szopinski^[15]	LT	103	54.1±15.3	103:0	54	41	8	A B C E I
Vupputuri^[16]	DT	62	49.97±13.25	62:0	不详	不详	不详	A B C D E F G
Vupputuri^[16]	LT	61	53.13±11.31	61:0	不详	不详	不详	A B C D E F G
Youssef^[17]	DT	71	45.97±10.69	69:2	49	22	0	A B C D E F G H
Youssef^[17]	LT	72	43.89±10.27	69:3	56	16	0	A B C D E F G H

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