To investigate the effect of laparoscopic preperitoneal hernia repair (TAPP) and open procedure (PLUG) on postoperative pain and trauma stress in patients with inguinal hernia at high altitude.

96 patients with inguinal hernia who were treated in our hospital from January 2017 to May 2018 were selected. They were divided into study group and control group according to different treatment methods, 48 cases in each, and which were treated with TAPP and open tension-free inguinal hernia repair surgery. The surgical indexes, postoperative pain and trauma stress indexes were compared, and the postoperative complications were recorded.

The operation time in the study group was longer than that in the control group, and the blood loss, postoperative exhaust time, and postoperative hospital stay were significantly shorter than those in the control group (all P<0.05). At 12 h, 24 h, and 3 days after operation, the VAS scores in the study group were significantly lower than those in the control group (all P<0.05). The serum CRP, cortisol and IL-6 3 days after operation were significantly higher than before operation (P<0.05); the study group were significantly lower than the control group (all P<0.05). Patients in the 2 group had postoperative urinary retention (2.08% vs. 4.17%), inguinal seroma (29.17% vs. 22.92%), scrotal hematoma (2.08% vs. 4.17%), recurrence (0% vs. 2.08%) and incision infection(0% vs. 2.08%). No chronic pain case was observed in both 2 groups. There was no significant difference between the two groups (P>0.05).

TAPP treatment of inguinal hernia at high altitude can significantly reduce intraoperative bleeding and postoperative pain and reduce the body's trauma stress response, but the operation time is longer and the corresponding medical costs increase. Therefore, the clinical method should be selected according to the specific conditions of patients.