To explore the influence factors for the development of parastomal hernia in rectal cancer patients after Miles operation.

In a retrospective study, the clinical data of 84 rectal cancer patients who underwent Miles operation at the department of gastrointestinal surgery of the First Affiliated Hospital of Anhui Medical University between January 2016 and January 2019 were analyzed. The univariate analysis and binary logistic regression analysis were used to analyze relevant influence factors for the development of parastomal hernia.

Of 84 patients, 16 patients occurred parastomal hernia during the follow-up period, and the incidence of parastomal hernia was 19%. The univariate analysis showed that there were statistically significant differences in BMI and alpha-fetoprotein levels between parastomal hernia group and the non-parastomtal hernia group (P<0.05). Besides, the differences in comorbidities of disease, tumor stage and postoperative hypoalbuminemia between the two groups of subjects were very close to a significant level (0.05<P<0.1). The binary logistic regression analysis showed that BMI (>25 kg/m2) was significantly related to the development of parastomtal hernia [OR=6.784, β=1.915, 95% CI (1.979-23.263), P=0.002]; in addition, a postoperative hypoalbuminemia may be a potential factor for the development of parastomtal hernia [OR=3.501, β=1.253, 95% CI (0.989-12.388), P=0.052].

For overweight and obese patients (BMI>25 kg/m2), whose preoperative weight should be controlled reasonably; meanwhile, the nutritional status of patients at postoperative nutritional risk should be improved actively to avoid the development of parastomtal hernia.