To study the clinical effect of the application of the self-gripping mesh for inguinal hernia repair under local anesthesia and epidural anesthesia.

The clinical data of 100 patients treated by using the self-gripping mesh in the Anhui No.2 Provincial People's Hospital between February 2014 and October 2018 were retrospectively collected. They were divided into the local anesthesia group (n=80) and the epidural anesthesia group (n=20). The postoperative operation index, pain score, hospitalization index, postoperative complications and recurrence were compared between the two groups. And the levels of inflammatory factors before operation and 1 week after operation were compared between the two groups. The measurement data are expressed using (±s) and compared using t tests. The counting data are represented by frequency, compared χ² tests or Fisher tests.

The operation time of the local anesthesia group was longer than that of the epidural anesthesia group, and the leaving bed time and eat time of the local anesthesia group was shorter than those of the epidural anesthesia group, with significant differences (P<0.05). The postoperative 4 h visual analogue scale scores of the two groups had no statistical difference (P>0.05), and the hospital stay and cost in the local anesthesia group were less than those of the epidural anesthesia group, with significant differences (P<0.05). The incidence of postoperative urine retention in the local anesthesia group was lower than that of the epidural anesthesia group, with significant differences (P<0.05). However, the postoperative incision infection rate and the postoperative recurrence rate of the two groups were not statistically different (P>0.05). At 1 week after operation, the levels of interleukin-6, and tumor necrosis factor-α in the two groups decreased, and those of the local anesthesia group was lower than those of the epidural anesthesia group, with significant differences (P<0.05).

The application of the self-gripping mesh in the inguinal hernia repair under local anesthesia can effectively inhibit the early postoperative inflammatory reaction of the patient, promote the postoperative rehabilitation, and also can reduce the treatment burden of the patient, reduce the occurrence of the urine retention, and the pain-relieving effect of the two patients is comparable, which is worth for clinical promotion.