Seroma formation is a common occurrence following inguinal hernia repair. Most patients achieve favorable outcomes with appropriate observation and management. However, some patients may misinterpret a postoperative seroma as hernia recurrence, leading to unnecessary confusion and anxiety, and undermining confidence in prognosis. In a small proportion of cases, severe seromas that are inadequately managed may progress to local infection or other more complex complications, adversely affecting clinical outcomes. Therefore, an in-depth understanding of the etiologies and intervention strategies for postoperative seroma is essential to improve patient satisfaction and therapeutic effectiveness. In this article, we synthesize evidence from domestic and international literature to review the mechanisms underlying seroma formation, as well as current approaches to its prevention and treatment, with the aim of providing clinically applicable strategies for effective management.