To evaluate the safety and efficacy of a novel basement membrane–small intestinal submucosa (BM-SIS) composite biopatch for the repair of contaminated or infected inguinal hernias.

This single-center retrospective study included 24 patients with contaminated or infected inguinal hernias who underwent laparoscopic transabdominal preperitoneal (TAPP) repair in the Department of Gastrointestinal Surgery, Shanghai Pudong Hospital, between January 2023 and December 2024. All surgeries were performed using the BM-SIS composite biopatch. Perioperative and postoperative follow-up data were collected to analyze the incidence of postoperative complications and hernia recurrence.

All surgeries were completed successfully. The mean operative time was (112.92±36.43) min, and the median postoperative hospital stay was 7 (6, 10) days. There were no cases of mesh removal due to infection during the perioperative period. Postoperative complications included one case of seroma (4.2%), one case of incisional hernia (4.2%), one case of adhesive intestinal obstruction, and one case of small bowel perforation; all were managed with conservative or surgical treatment. No hernia recurrence was observed during a median follow-up of 14.5 (8.5, 21.5) months.

The BM-SIS composite biopatch demonstrates structural innovation, combining anti-infection properties and mechanical stability, making it a safe and effective clinical option for contaminated or infected inguinal hernia repair. However, long-term efficacy warrants validation through larger-scale studies.