Effect on testicular blood flow, level of testosterone and leukocyte count in patients with unilateral indirect inguinal hernia using TEP

doi:10.3877/cma.j.issn.1674-392X.2021.05.013

Abstract

Abstract:

Objective

To explore the effect on testicular blood flow, level of testosterone and leukocyte count in patients with unilateral indirect inguinal hernia using laparoscopic totally extraperitoneal repair (TEP).

Methods

96 patients with unilateral indirect inguinal hernia underwent TEP from January 2017 to December 2018 in our hospital were selected to collect the relevant clinical data. The testicular volume, level of plasma testosterone, testicular blood flow and leukocyte count were compared before operation, 3 day after operation, 3 months after and 6 months after operation.

Results

There were no significant changes in the testicular volume and levels of plasma testosterone before operation, 3 day after operation, 3 months after operation and 6 months after operation (P>0.05). 3 days after operation, the leukocyte count was higher than that before operation (P<0.05), 3 months after operation, the leukocyte count was higher than that 3 days after operation (P<0.05), and the leukocyte count in 6 months after operation was lower than that in 3 months after operation (P<0.05), but there was no significant difference compared with that before operation (P>0.05). 3 days after operation, 3 and 6 months after operation, the resistance index (RI) of internal testicular artery (ITA) and testicular artery (TA) were lower than that before operation (P<0.05), and the RI of ITA at 3 months after operation was lower than that at 3 days after operation (P<0.05), the RI of ITA at 6 months after operation was lower than that at 3 months after operation (P<0.05). 3days after operation, 3 months and 6 months after operation, the end-diastolic blood flow velocity (EDV) of testicular capsular artery (CA) were higher than that before operation, while the RI of CA was lower than that before operation (P<0.05). There were no significant changes in peak systolic blood flow velocity (PSV) of TA, CA and ITA before and after operation (P>0.05).

Conclusion

TEP procedure can improve testicular blood perfusion in patients with unilateral indirect inguinal hernia, without affecting the level of plasma testosterone and causing chronic inflammatory reaction, which is safe and reliable.

Key words: indirect inguinal hernia, testicular blood flow, testosterone, white blood cell, totally extraperitoneal repair

Qiwen Luo, Yonghong Dong, Weili Lin, Ziliang Wang, jun Xu. Effect on testicular blood flow, level of testosterone and leukocyte count in patients with unilateral indirect inguinal hernia using TEP[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2021, 15(05): 497-501.

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Figures/Tables 3

References 19

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时间	例数	血浆睾酮水平(μg/L)	睾丸体积(cm²)
术前	96	532.2±117.4	8.8±2.4
术后3 d	96	530.3±119.7	9.0±2.6
术后3个月	96	526.3±123.5	9.1±2.8
术后6个月	96	538.1±122.3	9.2±3.7
F值		0.114	0.229
P值		0.892	0.796

时间	例数	血浆睾酮水平(μg/L)	睾丸体积(cm²)
术前	96	532.2±117.4	8.8±2.4
术后3 d	96	530.3±119.7	9.0±2.6
术后3个月	96	526.3±123.5	9.1±2.8
术后6个月	96	538.1±122.3	9.2±3.7
F值		0.114	0.229
P值		0.892	0.796

时间	例数	白细胞计数(10⁹/L)	睾丸内动脉
时间	例数	白细胞计数(10⁹/L)	收缩期峰值血液流速(cm/s)	舒张末期血流速度(cm/s)	血管阻力指数
术前	96	5.2±0.3	4.5±0.6	2.6±0.4	0.4±0.1
术后3 d	96	9.6±1.6^*	4.6±0.6	2.7±0.4	0.3±0.1^*
术后3个月	96	6.3±0.4^**	4.7±0.7	2.8±0.5	0.3±0.2^*
术后6个月	96	5.4±0.2^#	4.8±0.8	2.9±0.3	0.3±0.1^*#
F值		170.483	0.966	2.880	8.000
P值		<0.001	0.383	0.059	<0.001

时间	例数	白细胞计数(10⁹/L)	睾丸内动脉
时间	例数	白细胞计数(10⁹/L)	收缩期峰值血液流速(cm/s)	舒张末期血流速度(cm/s)	血管阻力指数
术前	96	5.2±0.3	4.5±0.6	2.6±0.4	0.4±0.1
术后3 d	96	9.6±1.6^*	4.6±0.6	2.7±0.4	0.3±0.1^*
术后3个月	96	6.3±0.4^**	4.7±0.7	2.8±0.5	0.3±0.2^*
术后6个月	96	5.4±0.2^#	4.8±0.8	2.9±0.3	0.3±0.1^*#
F值		170.483	0.966	2.880	8.000
P值		<0.001	0.383	0.059	<0.001

时间	例数	睾丸动脉			睾丸包膜动脉
时间	例数	收缩期峰值血液流速(cm/s)	舒张末期血流速度(cm/s)	血管阻力指数	收缩期峰值血液流速(cm/s)	舒张末期血流速度(cm/s)	血管阻力指数
术前	96	10.5±2.6	4.3±1.2	0.6±0.1	6.6±1.3	2.8±0.5	0.6±0.1
术后3 d	96	10.6±2.5	4.7±1.1	0.5±0.1^*	6.6±1.2	3.4±0.6^*	0.5±0.1^*
术后3个月	96	10.9±2.5	4.9±1.3	0.5±0.2^*	6.7±1.2	3.3±0.7^*	0.5±0.2^*
术后6个月	96	10.7±2.4	4.6±1.4	0.5±0.1^*#	6.8±1.3	3.2±0.6^*	0.5±0.1^*
F值		0.307	2.546	8.00	0.299	9.164	8.000
P值		0.736	0.082	0.000	0.742	0.000	0.001

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