To study the efficacy and safety of laparoscopic totally extra-peritoneal (TEP) on serum gastrin and motilin for elderly patients with inguinal hernia.

120 elderly patients with inguinal hernia admitted to our hospital from January 2018 to December 2019 were divided into the experiment group and the control group according to random number table method, 60 cases in each group. The control group underwent open tension-free inguinal hernia repair, the experiment group performed TEP. The clinical parameters of the 2 groups, the levels of serum gastrin (GAS) and motilin (MOL) before and after operation were compared, the postoperative complications and recurrence were recorded.

Compared with the control group, the operation time, postoperative pain duration and hospitalization duration of the experiment group significantly shortened, the intraoperative blood loss significantly reduced, the postoperative spontaneous activity time significantly advanced (P<0.05). The levels of serum GAS and MOL 3 d after operation in the control group were significantly lower than those before operation, and significantly lower than those in the experimental group (P<0.05). The incidence of total complications in the control group was significantly higher than that in the experiment group (P<0.05). During the follow-up of 12 months, there was 1 recurrence in the control group, and there was no recurrence in the experiment group.

TEP in the treatment of elderly patients with inguinal hernia can significantly shorten the operation time, reduce intraoperative bleeding and postoperative pain, which is conducive to the recovery of postoperative gastrointestinal motility.