To investigate the difference of anesthesia effect between quadratus lumbarum block and transversus abdominis plane block guided by ultrasound in inguinal hernia repair.

From August 2018 to August 2020, 56 patients with inguinal hernia repair in Inner Mongolia Baogang Hospital were selected. 28 patients with ultrasound-guided transversus abdominis plane block were served as control group, and 28 patients with ultrasound-guided quadratus lumbarum block were used as observation group. The hemodynamic indexes (MAP, HR, SpO₂ before anesthesia, at the beginning of surgery, at 15, 30 minutes during the surgery), dexmedetomidine dosage, cases number of lidocaine used, pain score (VAS) at 4, 8, 12, 24, 48 hours, serum inflammatory factor index [C-reactive protein (CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α)], and postoperative complications were compared between the two groups.

There were no significant differences in MAP, HR and SpO₂ between the two groups before anesthesia, at the beginning of operation, 15 and 30 minutes during operation (P>0.05). There were no significant differences in the dosage of dexmedetomidine used and the number of cases of lidocaine used between the two groups (P>0.05). The VAS score of the observation group at 24 and 48 hours after operation was lower than those of the control group (P<0.05). There were no significant differences in VAS score between the two groups at 4, 8 and 12 hours (P>0.05). The levels of CRP, IL-6 and TNF-α in both groups were increased on the 1st day after operation (P<0.05). However, the levels of CRP, IL-6 and TNF-α in the observation groupat 1st day after operation were lower than those in the control group (P<0.05). There was no significant difference in the incidence of postoperative complications between the two groups (P>0.05).

For patients undergoing inguinal hernia repair surgery, ultrasound-guided transversus abdominis plane block and quadratus lumbarum block can obtain ideal anesthesia effect. The heart rate and blood pressure data of patients can be maintained stable during the operation, and both have good safety. Quadratus lumbarumblock can last longer analgesic effect after operation, and it is more conducive to stabilize the level of serum inflammatory factors.