To analyze the therapeutic effect of laparoscopic combined with open mesh repair on patients with abdominal incisional hernia.

A retrospective analysis of 133 patients with abdominal incisional hernia treated in Hubei Cancer hospital from February 2011 to February 2018, 62 patients underwent open mesh repair, as a control group, the remaining 71 patients underwent laparoscopic surgery combined with open mesh repair, as an observation group; observe the patient's surgical status, postoperative recovery, at 1st day after surgery detect serum oxidative stress indicators, including insulin (InS), β-endorphin (β-EP), levels of growth hormone (GH) and total antioxidant capacity (T-AOC). The patients were followed up for 1 year. The postoperative complications and recurrence rate were recorded.

The blood loss of the observation group was lower than that of the control group (P<0.05). The time of getting out of bed, the recovery time of bowel function, the first feeding time, the recovery time of bowel sounds and the hospital stay in observation group was lower than those in the control group (P<0.05). The serum levels of InS, GH and T-AOC in the observation group were higher than those in the control group, and the β-EP content was lower than the control group, with statistical significance (P<0.05); the incidence of complications in the observation group was lower than that in the control group (P<0.05).

Laparoscopic combined with open mesh repair is effective in patients with giant incisional hernia and intestinal adhesions. The patients have small trauma, rapid recovery, and the postoperative complications and recurrence rate are reduced.