To explore the effects of dexmedetomidine on the hemodynamics and anesthesia resuscitation of patients receiving laparoscopic inguinal hernia repair.

A total of 106 patients who underwent laparoscopic inguinal hernia repair in Hefei Cancer Hospital, Chinese Academy of Sciences from February 2019 to September 2023 were enrolled. They were divided into dexmedetomidine group (n=53) and traditional anesthesia group (n=53) by random number table method. The heart rate, blood pressure, respiratory function, anesthesia recovery index, anesthetic dosage and patient satisfaction were compared between the two groups.

At 15 min of pneumoperitoneum, the heart rate and blood pressure in the dexmedetomidine group were lower than those in the traditional anesthesia group [heart rate (65.4±8.1) times/min vs. (72.3±9.4) times/min, systolic blood pressure (95.4±11.3) mmHg vs. (103.2±12.5) mmHg, diastolic blood pressure [(61.7±7.6) mmHg vs. (68.4±8.3) mmHg, mean arterial pressure (77.1±9.2) mmHg vs. (84.6±10.1) mmHg], the differences were statistically significant (P<0.05). The respiratory function of the two groups was within the normal range, and there was no statistically significant difference between the two groups (P>0.05). The related indexes of anesthesia recovery in dexmedetomidine group were lower than those in traditional anesthesia group [postoperative recovery time (10.3±2.6) min vs. (13.1±2.8) min, incidence of emergence agitation (3.8% vs. 18.7%), spontaneous breathing recovery time (7.3±1.7) min vs. (8.2±1.9) min, postoperative extubation time (12.6±2.4) min vs. (15.3±2.7) min, VAS score at anesthesia recovery (2.2±0.5) points vs. (2.7±0.9) points], the differences were statistically significant (P<0.05). The dosage of anesthetic in the dexmedetomidine group was lower than that in the traditional anesthesia group, which were (360.3±35.9) μg and (426.7±40.6) μg, respectively. The satisfaction of patients in the dexmedetomidine group was higher, (92.4±5.1) points, and the traditional anesthesia group was (84.7±6.2) points, the difference was statistically significant (P<0.05).

Compared with traditional anesthesia methods, application of dexmedetomidine in laparoscopic inguinal hernia repair can make the patient's hemodynamics more stable and have certain advantages in anesthesia resuscitation.