To observe the effect of porcine small intestine submucosa mesh versus bovine pericardium mesh on the treatment of inguinal hernia with open tension-free hernia repair. To investigate the clinical value of different types of biological mesh on the treatment of inguinal hernia and to analyze the two types of biological meshes.

The data of 86 patients with inguinal hernia treated with two types of biological meshes undergoing open tension-free hernia repair from May 2016 to January 2018 in Fangta hospital of Traditional Chinese Medicine were retrospectively analyzed. These patients were divided into two groups according to different types of biological meshes. The surgical indexes, hospitalization indexes and complications of the two groups were observed. The safety and short-term efficacy of different types of biological meshes in the treatment of inguinal hernia were compared.

Of the 86 patients, 46 patients underwent porcine small intestine submucosa mesh and 40 patients underwent bovine pericardium mesh. No statistical difference was observed in operation time, hospital stay, postoperative pain score, postoperative complications between two groups (all P>0.05). No foreign body sensation, recurrence, chronic pain, and intestinal related complications were found in all patients.

Both porcine small intestine submucosa mesh and bovine pericardium mesh are safe and feasible for the treatment of inguinal hernia in open tension-free hernia repair.