To investigate the effect of anti-reflux effect and quality of life in patients with gastroesophageal reflux disease (GERD) complicated with hiatal hernia (HH) using laparoscopic hiatal hernia repair combined with fundoplication.

78 patients with gastroesophageal reflux disease complicated with hiatal hernia in the inpatient department of the digestive department from Xinjiang Uygur Municipal People's hospital from March 2015 to August 2017 were selected and divided into the observation group (42 cases) with laparoscopic hiatal hernia repair combined with fundoplication and the control group (36 cases) with traditional laparotomy. The operation status, postoperative adverse reactions, RDQ and GLQI scores were selected and compared between two groups.

The blood loss during the operation, the time of the operation, hospital-staying time and recovery time of intestinal function in in the observation group were lower than those in the control group, with statistical significance between the two groups (P<0.05). The RDQ scores in the observation group was lower than that in the control group, while the GLQI score was higher than that in the control group, with statistical significance between the two groups (P<0.05). However, there was no statistical difference in the adverse reactions between the two groups (P>0.05).

Laparoscopic hiatal hernia repair combined with fundoplication is a better method for patients with gastroesophageal reflux disease complicated with hiatal hernia, with better anti-reflux effect and better quality of life, which is worthy for further clinical application.