To investigate the clinical application of colostomy reduction combined with the placement of biological mesh to prevent stomal site incisional hernia.

Clinical data of patients who underwent colostomy reduction combined with biological mesh placement in the Department of Colorectal Surgery of Nanjing Drum Tower Hospital from January 2022 to December 2023 were analyzed. Surgical time, intraoperative blood loss, postoperative hospital stays, follow-up time, etc. were recorded. The incidence of stomal site incisional hernia (SSIH) was observed, along with postoperative incision infection, mesh infection, hematoma, seroma, intra-abdominal bleeding, intra-abdominal organ injury, congestion in the surgical area, foreign body sensation in the surgical area, pain in the surgical area, urinary retention, etc.

Eighteen patients were included, all of whom had the mesh placed in the preperitoneal space (Onlay technique). The surgeries were successful, with postoperative pain well-controlled (either by oral medication or by intravenous analgesia). Significant improvement was observed within 3 days. And by around 7 days, patients were mostly back to normal. None of the patients developed SSIH, incision infection, mesh infection, hematoma, intra-abdominal bleeding, intra-abdominal organ injury, congestion in the surgical area, foreign body sensation in the surgical area, or urinary retention. One patient experienced seroma, which improved after one week of local drainage tube placement. The tube was successfully removed and the patient was discharged, with subsequent good recovery.

Colostomy reduction combined with biological mesh placement is a safe and effective method for preventing SSIH. It can be considered for clinical application in similar patients.