Abstract:
Objective
To analyze the sedative and analgesic effect and safety of sevoflurane and propofol combined with ketamine anesthesia in hernia repair.
Methods
A total of 86 inguinal hernia patients in Hanchuan People's Hospital from March 2019 to March 2021 were selected, and randomly divided into two groups by random number table method, with 43 patients in each group. The control group were given propofol + ketamine anesthesia, and the experimental group were given sevoflurane and propofol combined with ketamine anesthesia. The mean arterial pressure, heart rate, stress response index,excellent and good anesthesia rate, anesthesia index and total incidence of adverse reactions were compared between the two groups at different time points.
Results
At the time points of 5 minutes after skin incision, flipping the sheath or manage the hernia sac, and at the end of the surgery, the norepinephrine and heart rate of the experimental group were lower than those of the control group, and the differences were statistically significant (P＜0.05). The norepinephrine, epinephrine and renin of the experimental group were lower than those of the control group during anesthesia induction, and the differences were statistically significant (P＜0.05). The excellent and good rate of anesthesia in the experimental group (95.35%) was higher than that in the control group (69.77%). The onset time, consciousness recovery time and orientation recovery time in the experimental group were shorter than those in the control group, and the differences were statistically significant (P＜0.05). There was no significant difference in the total incidence of adverse reactions between the experimental group and the control group (P＞0.05).
Conclusion
Sevoflurane and propofol combined with ketamine anesthesia in hernia repair can achieve ideal analgesic and sedative effects,maintain the stability of vital signs, and have a low incidence of adverse reactions.
Key words:
Sevoflurane,
Propofol,
Ketamine,
Herniorrhaphy,
Anesthetic effect,
Adverse reactions
Yan He, Wencai Xiang. Sedative and analgesic effect and safety of sevoflurane and propofol combined with ketamine anesthesia in hernia repair[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(05): 566-569.