Application of dexmedetomidine in ventriculo-peritoneal shunt and its effect on postoperative recovery of patients

doi:10.3877/cma.j.issn.1674-392X.2022.05.021

Abstract

Abstract:

Objective

To analyze the effect of dexmedetomidine on the recovery quality of children after inguinal hernia surgery.

Methods

Fifty-six children who underwent laparoscopic anesthesia with sevoflurane anesthesia and high-level ligation of the hernia sac in our hospital from April 2016 to May 2018 were enrolled. The random number table method was divided into two groups: the control group and the observation group, with 28 cases in each group. The observation group was given dexmedetomidine intravenous pumping, and the control group was given saline pumping. The heart rate (HR) at 4 time points before anesthesia induction (T1), after pumping dexmedetomidine load (T2), 10 minutes after surgery (T3), and after surgery (T4) and mean arterial pressure (MAP), clinical indicators, analgesic and sedative effects, and adverse reactions were analyzed.

Results

At the T1 time before induction of anesthesia, there was no significant difference in HR and MAP between the two groups (P>0.05). At T2, the HR of the observation group was lower than that of the control group (P<0.05). At the time points of T3 and T4, the HR and MAP of the observation group were significantly lower than those of the control group (P<0.05). The time of sleep in the observation group was significantly shorter than that of the control group (P<0.05). In the observation group, the agitation score and FLACC score were significantly lower than those in the control group (P<0.05), and the Ramsay score was significantly higher than the control group (P<0.05); the incidence of adverse reactions in the observation group was lower than that of the control group.

Conclusion

The application of dexmedetomidine in inguinal hernia in children can significantly exert the effect of analgesic sedative and hypnosis, maintain vital signs in children, which has a low incidence of adverse reactions, and have a good quality of recovery.

Key words: Hernia, inguinal, Herniorrhaphy, Children, Anesthesia, Vital signs

Zihao Wang, Yingpeng Ha. Application of dexmedetomidine in ventriculo-peritoneal shunt and its effect on postoperative recovery of patients[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2022, 16(05): 583-586.

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References 18

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组别	年龄(岁,±s)	性别[例(%)]		体质量指数(kg/m²,±s)	疝分类[例(%)]			疝分型[例(%)]			手术方式[例(%)]
组别	年龄(岁,±s)	男	女	体质量指数(kg/m²,±s)	斜疝	直疝	股疝	Ⅰ	Ⅱ	Ⅲ	高位疝囊结扎	联合内环缝缩术	联合筋膜修补术
观察组	4.57±1.44	15(53.6)	13(46.4)	14.23±2.11	10(35.7)	14(50.0)	4(14.3)	16(57.1)	9(32.1)	3(10.7)	20(71.4)	6(21.4)	2(7.1)
对照组	4.77±1.14	17 (60.7)	11(59.3)	14.55±2.43	8(28.6)	16(57.1)	4(14.3)	18(64.3)	8(28.6)	2(7.1)	22(78.6)	5(17.9)	1(3.6)
χ²/t值	0.576	0.291		0.526	0.355			0.376			0.519
P值	0.566	0.589		0.600	0.837			0.828			0.771

组别	年龄(岁,±s)	性别[例(%)]		体质量指数(kg/m²,±s)	疝分类[例(%)]			疝分型[例(%)]			手术方式[例(%)]
组别	年龄(岁,±s)	男	女	体质量指数(kg/m²,±s)	斜疝	直疝	股疝	Ⅰ	Ⅱ	Ⅲ	高位疝囊结扎	联合内环缝缩术	联合筋膜修补术
观察组	4.57±1.44	15(53.6)	13(46.4)	14.23±2.11	10(35.7)	14(50.0)	4(14.3)	16(57.1)	9(32.1)	3(10.7)	20(71.4)	6(21.4)	2(7.1)
对照组	4.77±1.14	17 (60.7)	11(59.3)	14.55±2.43	8(28.6)	16(57.1)	4(14.3)	18(64.3)	8(28.6)	2(7.1)	22(78.6)	5(17.9)	1(3.6)
χ²/t值	0.576	0.291		0.526	0.355			0.376			0.519
P值	0.566	0.589		0.600	0.837			0.828			0.771

组别	指标	T1	T2	T3	T4
观察组	HR（次/分）	102.25±4.22	95.35±4.12	96.24±4.23	100.27±4.34
对照组	HR（次/分）	101.33±4.25	100.43±4.32	104.15±5.44	107.55±5.63
t值		0.812	4.502	6.073	5.419
P值		0.419	0.000	0.000	0.000
观察组	MAP（mmHg）	72.13±3.14	73.11±3.83	75.46±4.69	75.28±4.13
对照组	MAP（mmHg）	71.62±4.16	72.22±4.56	78.93±5.54	80.76±5.43
t值		0.517	0.790	2.529	4.250
P值		0.606	0.432	0.014	0.000

组别	指标	T1	T2	T3	T4
观察组	HR（次/分）	102.25±4.22	95.35±4.12	96.24±4.23	100.27±4.34
对照组	HR（次/分）	101.33±4.25	100.43±4.32	104.15±5.44	107.55±5.63
t值		0.812	4.502	6.073	5.419
P值		0.419	0.000	0.000	0.000
观察组	MAP（mmHg）	72.13±3.14	73.11±3.83	75.46±4.69	75.28±4.13
对照组	MAP（mmHg）	71.62±4.16	72.22±4.56	78.93±5.54	80.76±5.43
t值		0.517	0.790	2.529	4.250
P值		0.606	0.432	0.014	0.000

组别	例数	手术时间(min)	拔管时间(h)	入睡时间(h)	苏醒时间(h)
观察组	28	28.55±10.39	15.08±5.59	13.42±4.02	19.26±3.34
对照组	28	27.34±12.47	13.87±4.47	20.33±5.43	18.24±4.53
t值		0.394	0.894	5.412	0.959
P值		0.695	0.375	0.000	0.341

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