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Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition) ›› 2021, Vol. 15 ›› Issue (05): 471-474. doi: 10.3877/cma.j.issn.1674-392X.2021.05.007

• Clinical Article • Previous Articles     Next Articles

Correlation between echocardiography and prognosis of neonates with congenital left diaphragmatic hernia

Gongquan Chen1, Jinyong Luo1, Qiong Qin1, Yu Liu1, Jinhui Yang1, Shuju Sun1,()   

  1. 1. Department of Ultrasound Imaging, Hubei Minzu University Affiliated Hospital, Enshi 445000, China
  • Received:2020-12-30 Online:2021-10-14 Published:2021-11-01
  • Contact: Shuju Sun

Abstract:

Objective

The purposeof this study was to explore the correlation between echocardiography results and the prognosis of neonates with congenital left diaphragmatic hernia, and to clarify the prognostic risk factors and protective factors of this disease, so as to provide reference for clinical decision making.

Methods

A total of 82 neonates born and treated with congenital left diaphragmatic hernia in our hospital from December 2017 to December 2020 were selected as the research objects for regression analysis.

Results

The proportion of hepatic herniation and mediastinal displacement in newborn infants who died was significantly higher than that in survivors (P<0.001). The inner diameter of the main pulmonary artery (MPA), the right pulmonary artery, RPA) and left ventricular dimension at the end of diastole (LVDd) were larger than those of newborn children, and the differences were statistically significant (P<0.05). Superhepatic herniation [OR=1.24, 95%CI (1.14, 1.43) ]and mediastinal displacement [OR=1.43, 95%CI (1.03, 1.45)] were independent risk factors for newborn infants with left diaphragmatic hernia (OR>1, P<0.05). MPA [OR=0.73, 95%CI (0.47, 0.93)], RPA [OR=0.45, 95%CI (0.37, 1.08)], LDVd [OR=0.52, 95%CI (0.21, 1.36)] was an independent protective factor for newborn infants with left diaphragmatic hernia (OR<1, P<0.05).

Conclusion

Hepatic herniation and mediastinal displacement are independent risk factors for newborn children with left diaphragmatic hernia, and the prognosis is poor. MPA, RPA and LDVd are independent protective factors for newborn infants with left diaphragmatic hernia, with a good prognosis. Echocardiography has certain clinical value in predicting the prognosis of children with congenital left diaphragmatic hernia.

Key words: Congenital left diaphragmatic hernia, Risk factors, Protective factors, Echocardiography

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