Analysis of clinical effect of different ways for prophylactic antibiotics in patients with incarcerated inguinal hernia repair

doi:10.3877/cma.j.issn.1674-392X.2021.02.014

Abstract

Abstract:

Objective

To explore the clinical effect of different ways for prophylactic antibiotics for patients with tension-free incarcerated inguinal hernia repair.

Methods

Prospectivelyselecting 96 patients who underwent tension-free inguinal hernia repair at Tianchang Traditional Chinese Medicine Hospital from May 2017 to January 2020. Forty-eight patients who received oral antibiotics for infection prevention served as the observation group, and 48 patients who received intravenous antibiotics for infection prevention served as the control group. The body temperature (preoperative, 1 d after surgery, 2 days after surgery, 3 days after surgery), changes in inflammatory indexes, length of postoperative hospital stay and postoperative infection-related complications were compared between the 2 groups.

Results

There was no significant difference in perioperative body temperature between the two groups (P>0.05). There was no statistically significant difference in inflammatory indexes between the two groups (P>0.05). The postoperative hospitalization time between the two groups was statistically significant (P<0.05), and the observation group was significantly shorter than the control group. There was no significant difference in postoperative infection-related complications between the two groups (P>0.05).

Conclusion

In patients with tension-free repair of incarcerated inguinal hernia, oral antibiotics do not increase postoperative infective-related complications and can shorten postoperative hospital stay compared with intravenous antibiotics.

Key words: Hernia, inguinal, Incarcerated, Hernia repair, Antibiotics, Infection, Oral

Zongbao Yang, Yuhua Lou. Analysis of clinical effect of different ways for prophylactic antibiotics in patients with incarcerated inguinal hernia repair[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2021, 15(02): 173-176.

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References 15

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组别	例数	男性性/女(例)	年龄(岁)	体质量指数(kg/m²)	嵌顿时间(h)	左侧/右侧(例)	ASA分级(例)
组别	例数	男性性/女(例)	年龄(岁)	体质量指数(kg/m²)	嵌顿时间(h)	左侧/右侧(例)	Ⅰ/Ⅱ/Ⅲ
对照组	48	47/1	59.17±11.31	21.42±3.65	6.33±2.04	20/28	22/20/6
观察组	48	46/2	60.29±11.53	20.96±3.81	6.77±2.32	23/25	21/23/4
χ²/t值		0.261^*	0.483	-0.184	1.011	0.379^*	0.447^*
P值		0.404	0.297	0.386	0.336	0.120	0.212

组别	例数	男性性/女(例)	年龄(岁)	体质量指数(kg/m²)	嵌顿时间(h)	左侧/右侧(例)	ASA分级(例)
组别	例数	男性性/女(例)	年龄(岁)	体质量指数(kg/m²)	嵌顿时间(h)	左侧/右侧(例)	Ⅰ/Ⅱ/Ⅲ
对照组	48	47/1	59.17±11.31	21.42±3.65	6.33±2.04	20/28	22/20/6
观察组	48	46/2	60.29±11.53	20.96±3.81	6.77±2.32	23/25	21/23/4
χ²/t值		0.261^*	0.483	-0.184	1.011	0.379^*	0.447^*
P值		0.404	0.297	0.386	0.336	0.120	0.212

组别	例数	术前1 d	术后1 d	术后2 d	术后3 d
对照组	48	36.32±0.45	36.91±0.41	37.09±0.51	36.69±0.48
观察组	48	36.35±0.51	37.02±0.56	37.11±0.48	36.78±0.52
t值		-0.306	-1.098	-0.188	-0.881
P值		0.397	0.886	0.319	0.573

组别	例数	术前1 d	术后1 d	术后2 d	术后3 d
对照组	48	36.32±0.45	36.91±0.41	37.09±0.51	36.69±0.48
观察组	48	36.35±0.51	37.02±0.56	37.11±0.48	36.78±0.52
t值		-0.306	-1.098	-0.188	-0.881
P值		0.397	0.886	0.319	0.573

组别	例数	术前				术后1 d				术后3 d
组别	例数	WBC(10⁹/L)	N(%)	CRP(mg/L)	PCT(ng/mL)	WBC(10⁹/L)	N(%)	CRP(mg/L)	PCT(ng/mL)	WBC(10⁹/L)	N(%)	CRP(mg/L)	PCT(ng/mL)
对照组	48	13.23±2.34	88.32±7.79	12.91±9.36	0.04±0.02	15.11±3.69	85.19±6.50	56.99±21.07	1.15±0.46	12.96±1.97	79.66±5.70	12.91±9.36	0.87±0.34
观察组	48	14.10±2.54	86.21±8.34	13.54±11.39	0.05±0.03	14.94±3.40	83.32±7.01	59.09±23.67	1.23±0.43	13.13±2.04	78.49±6.00	13.54±11.39	0.77±0.29
t值		2.679	1.349	1.877	0.193	1.239	2.394	4.267	2.337	3.086	2.775	1.590	2.444
P值		0.226	0.309	0.797	0.717	0.325	0.472	0.318	0.069	0.587	0.644	0.127	0.230

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