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Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition) ›› 2025, Vol. 19 ›› Issue (01): 25-30. doi: 10.3877/cma.j.issn.1674-392X.2025.01.005

• Review • Previous Articles    

Effect of different hernia patches on collagen deposition in wound healing

Yulin Huang1, Zhenling Ji1,()   

  1. 1.Department of General Surgery, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China
  • Received:2024-01-03 Online:2025-02-18 Published:2025-03-03
  • Contact: Zhenling Ji

Abstract:

As one of the common diseases in abdominal surgery, abdominal wall hernia often causes pain caused by the prolapse of the abdominal cavity organs, and even causes serious consequences such as organ necrosis, so more surgical treatment is needed.The fundamental reason for this is that a weak abdominal wall, collagen imbalance, or abnormal collagen fibers can lead to weakening and thinning of the connective tissue of the abdominal wall, which in turn can lead to the development and recurrence of hernias.Numerous studies have shown that the proportional dysregulation of type I / typeⅢ of collagen in the fascial tissue is the main factor involved in the inguinal hernia.It has been demonstrated that wound-healing collagen deposition is significantly affected by patch type , however, to date, no studies have investigated the role of different graft materials on collagen deposition and tissue remodeling in the human fascia.This article summarizes the effects of 3 types of hernia patches (non-absorbable patches,biological patches, and synthetic absorbable patches) on collagen deposition.

Key words: Abdominal wall hernia, Abdominal wall weakness, Collagen, Hernia patch

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