To explore the risk factors of postoperative seroma in adult scrotal hernia with laparoscopic transabdominal preperitoneal hernia repair (TAPP) and construct a prediction model.

A total of 219 patients who were admitted to People's Hospital of Lvliang City from July 2018 to December 2022 were selected as the research subjects, and analyzed the clinical data of the selected patients. Logistic regression analysis was used to screen the risk factors of seroma after laparoscopic TAPP repair. R software was used to complete the drawing of the nomogram prediction model. The receiver operating characteristic curve (ROC) were used to assess predictive model performance.

Among the selected 219 patients, 57 (26.0%) patients developed seroma. Univariate analysis showed that hernia history>5 years, operation time>90 min, hernia sac>6.0 cm, management of hernia sac, hernia sac neck shoulder scar were significantly correlated with seroma after laparoscopic TAPP scrotal hernia repair (P<0.05). Multivariate analysis showed that management of hernia sac and hernia sac>6.0 cm were independent risk factors for seroma after laparoscopic TAPP scrotal hernia repair. According to the multivariate logistic regression analysis results, the nomogram prediction model was constructed. The area under the ROC curve is 0.746 (95% CI 0.671-0.820).

Management of hernia sac and hernia sac>6.0 cm are independent risk factors for seroma in adult scrotal hernia with laparoscopic TAPP repair. Based on the above two independent risk factors, the established nomogram helps predict the risk of seroma in adult scrotal hernia with laparoscopic TAPP repair.