To explore the impact of clinical monitoring of antimicrobial drug use on perioperative prophylactic medication and the incidence of surgical site infections in inguinal hernia repair surgery.

A retrospective analysis was conducted on 389 patients with inguinal hernia treated at Lujiang Hospital of Traditional Chinese Medicine from July 2019 to July 2022. The patients were divided into two groups based on the method of antimicrobial drug use: Group A (196 patients from July 2019 to December 2020, before the monitoring of clinical use of antimicrobial drugs, routinely using antimicrobial drugs) and Group B (193 patients from January 2021 to July 2022, under the monitoring and intervention of clinical pharmacists in the pharmacy department, using antimicrobial drugs). All patients underwent transabdominal preperitoneal inguinal hernia repair surgery. The perioperative prophylactic use of antimicrobial drugs and the incidence of surgical site infections in both groups were statistically analyzed.

There were no significant differences in gender, age, or surgical site between the two groups (P>0.05). There were also no significant differences in the overall incidence of fever, wound healing time, or postoperative hospital stay between the two groups (P>0.05). The total use rate of antimicrobial drugs in Group A (61.22%) was higher than that in Group B (18.13%), with a statistical difference (P<0.05). The rates of surgical site infection in Groups A and B were 1.02% (2/196) and 1.55% (3/193), respectively, with no significant difference (P>0.05).

After the clinical monitoring of antimicrobial drugs, the use rate of antimicrobial drugs during the perioperative period of inguinal hernia repair surgery significantly decreased, while the incidence of surgical site infection and postoperative wound healing showed no significant change.