To investigate the effect and safety of laparoscopic tumor resection and immediate abdominal wall reconstruction for the abdominal wall aggressive fibromatosis in young women.

In the present study, we retrospectively analyzed the clinical, pathological and follow-up data of 12 patients with abdominal wall aggressive fibromatosis. All the patients underwent laparoscopic tumor resection and immediate abdominal wall reconstruction in the Department of Hernia and Abdominal Wall Surgery in Qilu Hospital of Shandong University from January 2020 to March 2023. The clinical characteristics, surgical related indicators and follow-up complications of the patients were analyzed.

All 12 patients were young women with a mean age of (32.33±6.02) years. Laparoscopic tumor resection and immediate abdominal wall reconstruction were successfully conducted in all patients, with a mean operative duration of (173.75±39.55) min. Six patients underwent full-thickness myofascial closure, two patients underwent partial-thickness myofascial closure, while four patients underwent partial suture to reduce the abdominal wall defect because the defect was large or located above the iliac bone. The mean size of abdominal wall defects after tumor resection was (9.79±2.94) cm × (8.21±2.93) cm, respectively. The mean area of mesh for defect repair was (259.58±62.35) cm². The median hospital stay was 11.50 days. The mean Numerical Rating Scale (NRS) score for pain on the third day after surgery was (2.42±1.00). The median follow-up duration was 16.50 months. During the follow-up period, seroma was found in 1 patient during postoperative CT examination; 3 patients had occasional local discomfort of abdominal wall, which had no significant impact on daily life; 1 patient had tumor recurrence 20 months after surgery. None of the patients died or had hematoma, surgical site/mesh infection, or abdominal wall hernia/bulge.

After fully preoperative evaluation, laparoscopic tumor resection combined with immediate abdominal wall reconstruction is feasible and safe for the treatment of abdominal wall aggressive fibromatosis in young women.