To analyze the outcome and its influencing factors of fetal congenital diaphragmatic hernia (FCHD).

To retrospectively analyze the data of fetal diaphragmatic hernia fetuses detected prenatal in Northwest Women and Children's Hospital from January 2015 to December 2019, including gestational age, number of left and right side, lung area to head circumference ratio (LHR), number of liver herniation cases, combined malformations and delivery. The combined malformations, gestational age, birth weight, treatment and outcome of neonates with diaphragmatic hernia after delivery were analyzed.

36% of FCHD had combined malformations, and at least 55% (71/128) cases were induced labor. The gestational age of the fetus with LHR<1.4 was earlier than those with LHR≥1.4. The gestational age of the fetus with combined malformations was earlier than those without combined malformations. The gestational age of the fetus with liver herniation is later than those without liver herniation. There was no statistically significant difference in LHR between fetuses with and without combined malformations, and fetuses with and without liver herniation, respectively. Liver herniation is more likely to be combined with other malformations in the fetus. There was no significant difference in the incidence of left and right sides with combined malformations. Of the 40 children delivered, there were seven at high risk and 4 cases of death.

Fetal diaphragmatic hernia has high proportion of combined malformations and high rate of induced labor. The cure rate of simple diaphragmatic hernia is high. The assess of fetal prognosis by the LHR and liver herniation should be further improved.