To analyze the efficacy and economic benefit of laparoscopic transabdominal preperitoneal prosthesis (TAPP) and hernia ring filling tension-free repair in the treatment of patients with inguinal hernias.

From January 2017 to February 2021, 100 patients with inguinal hernias who were admitted to the General Surgery Department of Suzhou First People's Hospital were divided into the control group and the research group, with 50 cases in each group. The method used was the random number table method. The control group received hernia ring filling for tension-free repair, and the research group received TAPP. Both groups were followed up until discharge. The perioperative indicators, pain and quality of life at different time points, inflammatory response and oxidative stress indicators before and 1 d after surgery, the incidence of complications during hospitalization, and economic benefits (hospitalization time, hospitalization costs) were compared between the two groups.

The intraoperative blood loss in the research group was lower in the two groups, and the time of surgery, postoperative ambulation, postoperative gastrointestinal function recovery, and postoperative return to normal activities was shorter in the two groups (P<0.05). At 6 h, 24 h, and 48 h after surgery, the scores of visual analog scale (VAS) of the two groups showed a decreasing trend, and the research group was lower in the two groups (P<0.05), the scores of short form36 (SF-36) showed an increasing trend, and the research group was higher between the two group (P<0.05). 1 d after surgery, the serum levels of tumor necrosis factor α (TNF-α), C-reactive protein (CPR), interleukin-6 (IL-6) and malondialdehyde (MDA) in the two groups were higher than those before surgery, but the research group was lower in the two groups (P<0.05); the serum level of superoxide dismutase (SOD) in the two groups were lower than those before surgery, but the research group was higher in the two groups (P<0.05). The incidence of complications in the research group during hospitalization was lower (8.00% vs 34.00%, P<0.05). The length of hospitalization time in the research group was shorter than that in the control group, and the hospitalization costs were higher than those in the control group (P<0.05).

Compared with hernia ring filling tension-free repair, TAPP in the treatment of inguinal hernias could reduce surgical trauma, promote postoperative recovery of patients, relieve pain, and improve the quality of life of patients, however, the cost of hospitalization was higher, and the treatment method could be selected considering the patient's condition and economic situation.