To compare the effects of polypropylene and polylactic acid composite mesh on the stress state of patients undergoing laparoscopic hernia repair and its therapeutic effect.

A total of 152 patients with inguinal hernia undergoing laparoscopic surgery in our hospital from December 2018 to June 2021 were selected as the research objects and randomly divided into control group (76 cases) and observation group (76 cases). The control group was treated with polypropylene mesh, and the observation group was treated with polypropylene and polylactic acid mesh. Operation time, intraoperative complications, postoperative hospital stay, postoperative time to get out of bed, hospitalization costs, postoperative pain, serum interleukin-6 (IL-6), C-reactive protein (CRP) levels and complications were compared between the two groups.

The operation time and hospitalization cost in the observation group were higher than those in the control group (P<0.05). At 1 d, 10 d, 1 month, and 3 months after surgery, VAS scores in both groups decreased gradually, and VAS scores in the observation group were lower than those in the control group (P<0.05). The serum IL-6 and CRP levels in both groups were significantly increased after operation compared with before operation (P<0.05), and the indexes in observation group were better than those in the control group (P<0.05). The total incidence of complications in the observation group was 3.59% (3/76), lower than the 9.21% (7/76) in the control group, but there was no statistical significance between the two groups (P>0.05). The recurrence rate was 0.00% (0/76) in the observation group and 1.32% (1/76) in the control group, and there was no significant difference between the two groups (P>0.05).

The use of self-immobilized polypropylene and polylactic acid composite mesh can reduce the postoperative stress reaction of patients, which does not increase and occur complications, which is conducive to postoperative recovery of patients, and can be popularized in clinical application.