To compare the treatment of infection following ventral henria tension-free repair by vacuum sealing drainage (VSD) and radical infection mesh resection.

A total of 63 patients with mesh infection after ventral hernia tension-free repair in affiliated hospital of North Sichuan Medical College from October 2013 to October 2018 were selected. According to the treatment plan given at that time, the patients were divided into radical infection mesh resection group and VSD group. In the radical infection mesh resection group, conventional infection mesh resection and abdominal wall reconstruction were performed, while in the VSD group, VSD materials were used for vacuum sealing drainage.

No recurrence was found in the VSD group, and 6 recurrences occurred in the radical infection mesh resection group. The difference was statistically significant (χ²=4.103, P=0.043). In the radical infection mesh resection group, 32 cases were cured and 1 case was ineffective. While in the VSD group, 28 cases were cured and 2 cases were ineffective. There was no significant difference in the cure rate of the two groups of patients (96.97% vs 93.33%, χ²=0.007, P=0.933).

Compared with radical infection mesh resection, VSD has the same treatment effectiveness and lower recurrence rate after treatment. At the same time, the operation is simple and reduces the operation risk and operation cost of patients. It is worthy of clinical application.