Study on risk factors and treatment of incisional hernia after renal transplantation

doi:10.3877/cma.j.issn.1674-392X.2019.05.003

Abstract

Abstract:

Incisional hernia is one of the most common postoperative complications in abdominal surgery. After abdominal organ transplantation, the risk of incisional hernia will increased due to long-term use of immunosuppression therapy and other reasons which lead delay wound healing and susceptibility to infection. The formation of incisional hernia after kidney transplantation is usually not fatal to patients, so it has not received much attention from surgeons. However, incisional hernia can lead to prolonged hospital stay and increased costs. In addition, if not treated promptly, the hernia contents may adhere to the hernia sac, which may lead to intestinal obstruction, cardiovascular and respiratory dysfunction; and it may seriously threaten the quality of life and physical health of patients. Therefore, the study of incisional hernia after kidney transplantation is particularly important.

Key words: Incisional hernia, Renal transplantation, Risk factor, Hernia mesh

Shan Su, Yingmo Shen. Study on risk factors and treatment of incisional hernia after renal transplantation[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2019, 13(05): 394-397.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhshfbwkzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.1674-392X.2019.05.003

https://zhshfbwkzz.cma-cmc.com.cn/EN/Y2019/V13/I05/394

References 40

[1]	Sevinc B, Okus A, Ay S, et al. Randomized prospective comparison of long-term results of onlay and sublay mesh repair techniques for incisional hernia[J]. Turk J Surg, 2018, 34(1): 17-20.
[2]	Shahida PA, Rameez AS, Akram R. Complication of onlay and sublay mesh plasty in ventral abdominal hernia repair[J]. J Surg Pak(Intern), 2015, 20(2): 48-51.
[3]	李骥宇，崔明，刘泽刚, 等. 直接穿刺法建立第一穿刺孔及气腹在腹腔镜切口疝修补术中的应用[J/CD]. 中华疝和腹壁外科杂志(电子版), 2019, 13(1): 36-38.
[4]	倪敏，申英末，刘静, 等. 肌后间隙修补法治疗腹壁切口疝患者的疗效[J/CD]. 中华疝和腹壁外科杂志(电子版), 2018, 12(5): 360-362.
[5]	Smith CT, Katz MG, Foley D, et al. Incidence and risk factors of incisional hernia formation following abdominal organ transplantation[J]. Surg Endosc, 2015, 29(2): 398-404.
[6]	Massarweh NN, Clayton JL, Mangum CA, et al. High body mass index and short-and long-term renal allograft survival in adults[J]. Transplantation, 2005, 80(10): 1430-1434.
[7]	Singh D, Lawen J, Alkhudair W. Does Pretransplant obesity affect the outcome in kidney transplant recipients?[J]. Transplant Proc, 2005, 37(2): 717-720.
[8]	Birolini C. Prosthetic repair of incisional hernia in kidney transplant patients. A technique with onlay polypropylene mesh[J]. Hernia, 2001, 5(1): 31-35.
[9]	Mahdavi R, Mehrabi M. Incisional Hernia after Renal Transplantation and Its Repair with Propylene Mesh[J]. Urol J, 2004, 1(4): 259-262.
[10]	Mazzucchi E, Nahas WC, Antonopoulos I, et al. Incisional hernia and its repair with polypropylene mesh in renal transplant recipients[J]. J Urol, 2001, 166(3): 816-819.
[11]	Varga M, Matia I, Kucera M, et al. Polypropylene mesh repair of incisional hernia after kidney transplantation: Single-center experience and review of the literature[J]. Ann Transplant, 2011, 16(3): 121-125.
[12]	Humar A, Ramcharan T, Denny R, et al. Are wound complications after a kidney transplant more common with modern immunosuppression? [J]. Transplantation, 2001, 72(12): 1920-1923.
[13]	Clemente Ramos LM, Burgos Revilla FJ, Gómez Dosantos V, et al. Reconstructive surgery with polypropylene mesh associated with kidney transplant[J]. Actas Urol Esp, 1998, 22(4): 320-325.
[14]	Flechner SM, Zhou L, Derweesh I, et al. The impact of sirolimus, mycophenolate mofetil, cyclosporine, azathioprine, and steroids on wound healing in 513 kidney-transplant recipients[J]. Transplantation, 2003, 76(12): 1729-1734.
[15]	Ooms L S, Verhelst J, Jeekel J, et al. Incidence, risk factors, and treatment of incisional hernia after kidney transplantation: An analysis of 1, 564 consecutive patients[J]. Surgery, 2016, 159(5): 1407-1411.
[16]	Mele TS, Halloran PF. The use of mycophenolate mofetil in transplant recipients[J]. Immunopharmacology, 2000, 47(2/3): 215-245.
[17]	Meier-Kriesche HU, Friedman G, Jacobs M, et al. Infectious complications in geriatric renal transplant patients: comparison of two immunosuppressive protocols[J]. Transplantation, 1999, 68(10): 1496-1502.
[18]	Filocamo MT, Zanazzi M, Marzi VL, et al. The Approach by Midline Incision for Extraperitoneal Kidney Transplantation[J]. Transplant Proc, 2007, 39(10): 3077-3080.
[19]	Knight RJ, Villa M, Laskey R, et al. Risk factors for impaired wound healing in sirolimus-treated renal transplant recipients[J]. Clin Transplant, 2007, 21(4): 460-465.
[20]	Troppmann C, Pierce JL, Gandhi MM, et al. Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation: a matched-pair pilot study[J]. Transplantation, 2003, 76(2): 426-429.
[21]	Cao W, Mohacsi P, Shorthouse R, et al. Effects of rapamycin on growth factor-stimulated vascular smooth muscle cell DNA synthesis. Inhibition of basic fibroblast growth factor and platelet-derived growth factor action and antagonism of rapamycin by FK506[J]. Transplantation, 1995, 59(3): 390-395.
[22]	Monte AIL, Damiano G, Maione C, et al. Use of Intraperitoneal ePTFE gore dual-mesh plus in a giant incisional hernia after kidney transplantation: a case report[J]. Transplant Proc, 2009, 41(4): 1398-1401.
[23]	O"Dwyer PJ, Courtney CA. Factors involved in abdominal wall closure and subsequent incisional hernia[J]. Surgeon, 2003, 1(1): 17-22.
[24]	Grantcharov TP, Rosenberg J. Vertical compared with transverse incisions in abdominal surgery[J]. Eur J Surg, 2001, 167(4): 260-267.
[25]	Greenall MJ, Evans M, Pollock AV. Midline or transverse laparotomy? A random controlled clinical trial. Part I: Influence on healing[J]. Br J Surg, 1980, 67(3): 188-190.
[26]	Nanni G, Tondolo V, Citterio F, et al. Comparison of Oblique Versus Hockey-Stick Surgical Incision for Kidney Transplantation[J]. Transplant Proc, 2005, 37(6): 2479-2481.
[27]	Yildız I, Koca YS. What kind of incision should be made to reduce the risk of incisional hernia in kidney transplantation?[J]. Ann Transplant, 2017, 22: 689-693.
[28]	Israelsson LA, Millbourn D. Prevention of incisional hernias how to close a midline incision[J]. Surg Clin North Am, 2013, 93(5): 1027-1040.
[29]	Högström H, Haglund U, Zederfeldt B. Suture technique and early breaking strength of intestinal anastomoses and laparotomy wounds[J]. Acta Chir Scand, 1985, 151(5): 441-443.
[30]	Usher FC, Ochsner J, Tuttle LL. Use of marlex mesh in the repair of incisional hernias[J]. Am Surg, 1958, 24(24): 969-974.
[31]	Clemente Ramos LM, Burgos Revilla FJ, Gómez Dosantos V, et al. Reconstructive surgery with polypropylene mesh associated with kidney transplant[J]. Actas Urol Esp, 1998, 22(4): 320-325.
[32]	Beasley KA, Mcalister VC, Luke PPW. Mesh hood fascial closure in renal allograft compartment syndrome[J]. Transplant Proc, 2003, 35(7): 2418-2419.
[33]	Antonopoulos IM, Nahas WC, Mazzucchi E, et al. Is polypropylene mesh safe and effective for repairing infected incisional hernia in renal transplant recipients?[J]. Urology, 2005, 66(4): 874-877.
[34]	Birolini C, Utiyama EM, Rodrigues AJ, et al. Elective colonic operation and prosthetic repair of incisional hernia: does contamination contraindicate abdominal wall prosthesis use?[J]. J Am Coll Surg, 2000, 191(4): 366-372.
[35]	Martin P, Barbora E, Andrej L, et al. Abdominal closure reinforcement by using polypropylene mesh functionalized with poly-ε-caprolactone nanofibers and growth factors for prevention of incisional hernia formation[J]. Int J Nanomedicine, 2014, 9(1): 3263-3277.
[36]	Jakubova R, Mickova A, Buzgo M, et al. Immobilization of thrombocytes on PCL nanofibres enhances chondrocyte proliferation in vitro[J]. Cell Prolif, 2011, 44(2): 183-191.
[37]	Chen M, Patra PK, Warner SB, et al. Role of Fiber Diameter in Adhesion and Proliferation of NIH 3T3 Fibroblast on Electrospun Polycaprolactone Scaffolds[J]. Tissue Eng, 2007, 13(3): 579-587.
[38]	Rampichová M, Chvojka J, Buzgo M, et al. Elastic three-dimensional poly(ε-caprolactone) nanofibre scaffold enhances migration, proliferation and osteogenic differentiation of mesenchymal stem cells[J]. Cell Prolif, 2013, 46(1): 23-37.
[39]	Ebersole GC, Buettmann EG, Macewan MR, et al. Development of novel electrospun absorbable polycaprolactone(PCL) scaffolds for hernia repair applications[J]. Surg Endosc, 2012, 26(10): 2717-2728.
[40]	Santangelo ML, Carlomagno N, Spiezia S, et al. Use of biological prostheses in transplant patients with incisional hernias. Preliminary experience[J]. Ann Ital Chir, 2013, 84(4): 471-475.

Please choose a citation manager

Content to export