总结复旦大学附属中山医院近3年腹壁肿瘤手术切除后腹壁缺损处理的治疗经验，为后续腹壁肿瘤的临床诊疗工作提供参考。

回顾性收集2022年1月至2025年3月于复旦大学附属中山医院因腹壁恶性及交界性肿瘤行手术治疗的39例患者的临床资料，整理并分析患者术前基础资料、腹壁肿瘤情况、手术以及术后恢复情况，进一步对腹壁肿瘤及手术因素对术后并发症的影响行单因素分析。

39例患者，腹壁恶性肿瘤病灶最大宽度平均（4.9±3.0）cm；腹壁缺损平均最大宽度（7.0±3.3）cm。腹壁缺损Ⅰ、Ⅱ、Ⅲ型分别为11、16、12例，以Ⅱ型缺损多见；缺损位于U区8例，M区10例，L区20例，M＋L区1例，以L区多见，占51.3%；缺损分级以1级缺损多见，占66.7%（26/39），2、3级缺损分别占7.7%（3/39）、25.6%（10/39）；术后病理见13种肿瘤类型；肿瘤多来源于原发性肿瘤，占46.2%（18/39）。肿瘤切除术后腹壁缺损修补采用单纯缝合20例、补片修补16例、皮瓣游离后重建腹壁3例。术后患者Clavien-DindoⅡ、Ⅲ级并发症发生率均为2.6%（1/39），无补片相关并发症发生，住院时间中位数为4（2，5）d，无出院后30 d内非计划再入院病例。随访发现出院后3个月内，30.8%（12/39）的患者出现肿瘤转移，21.3%（9/39）出现腹壁肿瘤复发，随访过程中无死亡病例。单因素分析发现3级腹壁缺损与术后并发症发生相关（P=0.043）。

腹壁肿瘤的临床处理复杂多变，需根据患者自身情况、肿瘤大小及疾病进展程度个体化选择修补方法与材料，本研究显示腹壁肿瘤切除术后使用补片修补腹壁缺损安全可靠，但未来仍需开展更多临床研究提供数据参考。

To summarize the treatment experience in reconstruction of abdominal wall defect following surgical resection of abdominal wall tumors in Zhongshan Hospital, Fudan University over the past three years, and to provide reference for subsequent clinical diagnosis and treatment of abdominal wall tumors.

Clinical data including patients' baseline characteristics, abdominal wall tumor characteristics, surgical details and postoperative recovery data from 39 patients who underwent surgical treatment for malignant and borderline abdominal wall tumors in Zhongshan Hospital, Fudan University between January 2022 and March 2025 were retrospectively collected, sorted, and analyzed. Further univariate analysis was conducted on the influence of abdominal wall tumors and surgical factors on postoperative complications.

Among the 39 patients, the average maximum width of malignant tumors in the abdominal wall was (4.9±3.0) cm, and the average maximum width of abdominal wall defects was (7.0±3.3) cm. There were 11, 16, and 12 cases of Type Ⅰ, Ⅱ, and Ⅲ abdominal wall defects respectively. Type Ⅱ defects were more common. There were 8 patients with defects located in the U-zone, 10 in the M-zone, 20 in the L-zone, and 1 in the M+L-zone, with the L area being the most common, accounting for 51.3%. Grade 1 defects were more common (66.7%, 26/39), grade 2 and 3 defects were 7.7% (3/39) and 25.6% (10/39), respectively. There were 13 types of tumors on postoperative pathology. Most of the tumors originated from primary tumors (46.2%, 18/39). Intraoperatively, 20 patients underwent simple suture closure, 16 received mesh repair, and 3 underwent free flap reconstruction of the abdominal wall after tumor resection. Postoperatively, the incidence of Clavien-Dindo Grade Ⅱ and Ⅲ complications were both 2.6% (1/39) and no mesh-related complications occurred. The median of hospital stay was 4 (2, 5) days, and no patients required unplanned readmission within 30 days after discharge. Within three months after discharge, 30.8% (12/39) of patients developed tumor metastasis, 21.3% (9/39) experienced abdominal wall tumor recurrence, and no patients died during follow-up. Univariate analysis found that grade 3 abdominal wall defect was associated with the occurrence of postoperative complications (P=0.043).

The clinical management of abdominal wall tumors is complicated and variable, because of diverse patient-specific factors, tumor size, and disease progression, which require individualized selection of repair methods and materials. This study shows that mesh repair for abdominal wall defects after tumor resection is safe and reliable, but further clinical studies are needed to provide additional data for reference.