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中华疝和腹壁外科杂志(电子版) ›› 2025, Vol. 19 ›› Issue (04) : 390 -395. doi: 10.3877/cma.j.issn.1674-392X.2025.04.005

所属专题: 文献

腹膜后肿瘤专题综述

腹膜后肿瘤临床诊疗现状
张海强, 周保军()   
  1. 050000 石家庄,河北医科大学第二医院普外二科
  • 收稿日期:2025-06-23 出版日期:2025-08-18
  • 通信作者: 周保军
  • 基金资助:
    2025年河北省政府资助临床医学优秀人才培养项目(ZF2025089)

Current status of clinical diagnosis and treatment for retroperitoneal tumors

Haiqiang Zhang, Baojun Zhou()   

  1. Department of General Surgery, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Received:2025-06-23 Published:2025-08-18
  • Corresponding author: Baojun Zhou
引用本文:

张海强, 周保军. 腹膜后肿瘤临床诊疗现状[J/OL]. 中华疝和腹壁外科杂志(电子版), 2025, 19(04): 390-395.

Haiqiang Zhang, Baojun Zhou. Current status of clinical diagnosis and treatment for retroperitoneal tumors[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2025, 19(04): 390-395.

腹膜后肿瘤(RPT)是一类罕见且异质性显著的疾病,以脂肪肉瘤和平滑肌肉瘤为主的恶性肿瘤占多数。其解剖位置深在、早期症状隐匿,诊断依赖CT/MRI等影像技术及穿刺活检。RPT临床治疗以外科手术为主,强调首次R0切除对预后的重要性,但受限于复杂解剖及高复发风险,需多学科协作制定个体化方案。放射治疗、化学治疗和靶向治疗等疗效甚微,且临床药物选择需根据具体病理类型而定。虽然RPT的治疗逐渐规范明确,但仍面临诸多挑战。本文旨在结合相关研究进展及最新指南,系统阐述RPT的诊疗现状,为临床治疗制定最佳策略提供参考。

Retroperitoneal tumors (RPT) represent a rare and highly heterogeneous group of diseases, with the majority being malignant neoplasms such as liposarcoma and leiomyosarcoma. Because of their deep-seated anatomical location and subtle early symptoms, diagnosis relies on techniques such CT/MRI and puncture biopsy confirmation. The cornerstone of RPT clinical treatment remains surgical resection, with emphasis on achieving initial R0 resection for prognostic optimization. However, treatment is challenged by complex anatomical constraints and high recurrence risks, multidisciplinary collaboration is required to formulate individualized treatment plans. Radiotherapy, chemotherapy, and targeted therapies demonstrate limited efficacy, and the clinical drug selection must be tailored to specific pathological subtypes. Although the treatment for RPT has become increasingly standardized and well-defined, it still faces numerous challenges. This article aims to systematically elaborate on the current diagnostic and treatment of RPT, integrating relevant research progress and the latest guidelines, to provide a reference for formulating optimal clinical treatment strategies.

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