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中华疝和腹壁外科杂志(电子版) ›› 2023, Vol. 17 ›› Issue (03) : 316 -321. doi: 10.3877/cma.j.issn.1674-392X.2023.03.017

论著

丙泊酚与七氟烷在老年腹股沟疝腹腔镜手术的应用效果及安全性比较
曾凯旋, 何国安()   
  1. 242300 安徽宣城,宁国市人民医院麻醉科
  • 收稿日期:2022-11-15 出版日期:2023-06-18
  • 通信作者: 何国安
  • 基金资助:
    宣城市科技计划项目(2235)

Efficacy and safety of propofol and sevoflurane in elderly patients undergoing laparoscopic inguinal hernia surgery

Kaixuan Zeng, Guoan He()   

  1. Department of Anesthesiology, Ningguo People's Hospital, Xuancheng 242300, Anhui, China
  • Received:2022-11-15 Published:2023-06-18
  • Corresponding author: Guoan He
引用本文:

曾凯旋, 何国安. 丙泊酚与七氟烷在老年腹股沟疝腹腔镜手术的应用效果及安全性比较[J/OL]. 中华疝和腹壁外科杂志(电子版), 2023, 17(03): 316-321.

Kaixuan Zeng, Guoan He. Efficacy and safety of propofol and sevoflurane in elderly patients undergoing laparoscopic inguinal hernia surgery[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2023, 17(03): 316-321.

目的

探讨丙泊酚、七氟烷应用于老年腹股沟疝腹腔镜手术的效果及安全性。

方法

选择2022年1—10月,宁国市人民医院收治的60~80岁腹股沟疝患者60例作为研究对象。依据随机数字表法分为观察组及对照组,各30例。观察组实施以七氟烷为核心的吸入和静脉输注麻醉方法,对照组实施以丙泊酚为核心的静脉输注麻醉方法。对比2组患者的心率变化情况、麻醉诱导时间、麻醉苏醒指标(术后苏醒时间、自主呼吸恢复时间、术后拔管时间、定向力恢复时间)、术后躁动及不良反应情况。

结果

对照组心率在切皮时低于观察组(P<0.05),其他各时间点,2组差异均无统计学意义(P>0.05)。2组麻醉诱导时间差异无统计学意义(P>0.05)。观察组术后苏醒时间、自主呼吸恢复时间、术后拔管时间、定向力恢复时间均短于对照组(P<0.05)。2组患者的手术时长、肌松药用量;术后发生躁动患者的比例和镇静躁动评分;术后不良反应发生率差异均无统计学意义(P>0.05)。

结论

腹腔镜腹股沟疝修补术中,采用丙泊酚及七氟烷均可以达到较为满意的麻醉效果,但七氟烷对心率的影响更小且苏醒质量更高,临床上在充分考虑患者客观情况的基础上,可优先使用。

Objective

To investigate the effect and safety of propofol and sevoflurane applied to laparoscopic inguinal hernia surgery in elderly patients.

Methods

From January to October 2022, 60 patients aged 60-80 years old with inguinal hernia treated at Ningguo City People's Hospital were selected as the research subjects. According to the random number table method, they were divided into an observation group and a control group, each with 30 cases. Patients in the observation group were given inhalation and intravenous infusion anesthesia with sevoflurane as the core, and patients in the control group were given intravenous infusion anesthesia with propofol as the core. The heart rate changes, anesthesia induction time, anesthesia awakening indexes (postoperative awakening time, recovery time of spontaneous breathing, postoperative extubation time, and recovery time of orientation), postoperative agitation, and postoperative adverse reactions of patients in the 2 groups were compared.

Results

The heart rate of the patients in the control group was lower than that of the patients in the observation group only at the time of skin incision (P<0.05). At other time points, there was no significant difference in heart rate data between the two groups (P>0.05). There was no significant difference in the data on anesthesia induction time between the two groups (P>0.05). The recovery time, spontaneous respiration recovery time, extubation time and directional force recovery time of patients in the observation group were shorter than those in the control group (P<0.05). There was no statistical difference between the two groups in the operation time and the dosage of muscle relaxant (P>0.05). There was no significant difference in the proportion of postoperative restlessness and the data of sedation restlessness score between the two groups (P>0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).

Conclusion

During laparoscopic inguinal hernia repair surgery, propofol and sevoflurane can achieve satisfactory anesthetic effects, but sevoflurane has a lower impact on heart rate and a higher quality of recovery, which can be used preferentially on the basis of fully considering the objective conditions of patients.

表1 Riker镇静躁动评分标准
表2 2组患者一般资料比较[例(%)]
表3 2组患者不同时间点的心率变化情况比较(次/min,±s
表4 2组患者的麻醉诱导时间及苏醒相关指标比较(min,±s
表5 2组患者术后躁动情况比较
表6 2组患者术后不良反应发生情况比较[例(%)]
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