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中华疝和腹壁外科杂志(电子版) ›› 2024, Vol. 18 ›› Issue (05) : 562 -565. doi: 10.3877/cma.j.issn.1674-392X.2024.05.017

论著

静注右美托咪定、利多卡因对腹腔镜疝修补术患者围手术期心率、麻醉苏醒质量的比较
张锋1,(), 孙孟奇1, 方秀春1   
  1. 1.236300 安徽阜阳,阜南县人民医院麻醉科
  • 收稿日期:2023-11-29 出版日期:2024-10-18
  • 通信作者: 张锋
  • 基金资助:
    阜阳市卫生健康委科研项目(FY2021-122)

Comparison of intravenous injection of dexmedetomidine and lidocaine on perioperative heart rate and anesthesia recovery quality in patient undergoing laparoscopic hernia repair

Feng Zhang1,(), Mengqi Sun1, Xiuchun Fang1   

  1. 1.Department of Anesthesiology, Funan County People's Hospital,Fuyang 236300,Anhui Province, China
  • Received:2023-11-29 Published:2024-10-18
  • Corresponding author: Feng Zhang
引用本文:

张锋, 孙孟奇, 方秀春. 静注右美托咪定、利多卡因对腹腔镜疝修补术患者围手术期心率、麻醉苏醒质量的比较[J]. 中华疝和腹壁外科杂志(电子版), 2024, 18(05): 562-565.

Feng Zhang, Mengqi Sun, Xiuchun Fang. Comparison of intravenous injection of dexmedetomidine and lidocaine on perioperative heart rate and anesthesia recovery quality in patient undergoing laparoscopic hernia repair[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2024, 18(05): 562-565.

目的

比较静注右美托咪定(Dex)、利多卡因(Lido)对腹腔镜疝修补术患者围手术期心率(HR)、麻醉苏醒质量。

方法

选取在2021 年1 月至2023 年8 月阜南县人民医院收治的80 例腹腔镜疝修补术患者,按随机数表法分为Dex组(静注Dex)和Lido组(静注Lido)。比较2组患者围手术期HR 及平均动脉压(MAP),术中平均七氟醚吸入浓度、拔管时间、苏醒时间、躁动发生率、躁动持续时间、药物补救次数及镇痛评分。比较2组术前及术后即刻疼痛应激生化指标,记录2组不良反应发生情况。

结果

2组围手术期HR 和MAP组间、时间点及交互差异均无统计学意义(P>0.05);Lido组术中平均七氟醚吸入浓度、拔管时间、苏醒时间均低于Dex组(P<0.05);2组躁动发生率、躁动持续时间、药物补救次数比较差异无统计学意义(P>0.05);2组在术后3、12 和24 h 镇痛评分比较差异无统计学意义(P>0.05);与术前相比,术后即刻2组血清超氧化物歧化酶(SOD)均降低(P<0.05)、丙二醛(MDA)均升高(P<0.05),但2组SOD 和MDA 比较,差异无统计学意义(P>0.05);2组不良反应发生情况比较,差异无统计学意义(P>0.05)。

结论

静注Dex 和Lido 对腹腔镜疝修补术患者均有较佳麻醉效果,血流动力学稳定,但Lido 可以缩短拔管时间,患者苏醒更快,更利于术后恢复。

Objective

To compare the effect of intravenous injection of dexmedetomidine (Dex)and lidocaine (Lido) on perioperative heart rate (HR) and anesthesia recovery quality in patient undergoing laparoscopic hernia repair.

Methods

Eighty patients undergoing laparoscopic hernia repair from January 2021 to August 2023 were selected and randomly divided into Dex group (intravenous injection of Dex)and Lido group (intravenous injection of Lido) according to random number table method. The perioperative HR, mean arterial pressure (MAP), intraoperative mean sevoflurane inhalation concentration,extubation time, recovery time, incidence rate of agitation, duration of agitation, number of drug remedy,and analgesia score were compared between the two groups. The pain stress biochemical indicators before and immediately after surgery were compared between the two groups, and the occurrence of adverse reactions were recorded.

Results

There were no statistically significant differences in perioperative HR and MAP from the aspects of between groups, time points and interaction (P>0.05). Compared with the Dex group, the Lido group had significantly lower intraoperative sevoflurane concentration, shorter extubation time and recovery time (P<0.05). There was no significant difference in the incidence rate of agitation, duration of agitation, number of drug remedy between the two groups (P>0.05). There was no significant significance in analgesia score between the two groups at 3 hours, 12 hours and 24 hours after surgery (P>0.05). Compared with before surgery, the serum superoxide dismutase (SOD) in both groups was decreased (P<0.05) while malondialdehyde (MDA) was increased (P<0.05), but the difference was not significant in SOD and MDA between the two groups (P>0.05). There was no statistically significant difference in adverse reactions between the two groups (P>0.05).

Conclusion

Intravenous injection of Dex and Lido for patients undergoing laparoscopic hernia repair have good anesthesia effect and stable perioperative hemodynamics. However, Lido has shorter extubation time, and faster recovery, and is more conducive to postoperative recovery.

表1 2组患者一般资料比较
表2 2组患者围手术期血流动力学比较(±s
表3 2组患者术中平均七氟烷吸入浓度、拔管时间、苏醒时间比较(±s
表4 2组患者躁动发生率、躁动持续时间、药物补救次数比较
表5 2组患者镇痛评分比较(分,±s
表6 2组患者疼痛应激生化指标比较(±s
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