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中华疝和腹壁外科杂志(电子版) ›› 2021, Vol. 15 ›› Issue (04) : 325 -328. doi: 10.3877/cma.j.issn.1674-392X.2021.04.003

综述

疝外科网片在盆腔脏器脱垂治疗中的应用现状及展望
马懿迪1, 王素美1,()   
  1. 1. 100020 北京,首都医科大学附属北京朝阳医院妇产科
  • 收稿日期:2021-02-05 出版日期:2021-08-18
  • 通信作者: 王素美

Application status and prospect from hernia surgical mesh in the treatment of pelvic organ prolapse

Yidi Ma1, Sumei Wang1,()   

  1. 1. Department of Obstetrics and Gynecology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
  • Received:2021-02-05 Published:2021-08-18
  • Corresponding author: Sumei Wang
引用本文:

马懿迪, 王素美. 疝外科网片在盆腔脏器脱垂治疗中的应用现状及展望[J]. 中华疝和腹壁外科杂志(电子版), 2021, 15(04): 325-328.

Yidi Ma, Sumei Wang. Application status and prospect from hernia surgical mesh in the treatment of pelvic organ prolapse[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2021, 15(04): 325-328.

盆腔脏器脱垂(POP)的治疗中使用经阴道植入网片引起了较多争议,其在为患者提供有效微创治疗的同时也导致了严重的网片相关并发症的发生。不良网片相关并发症是由网片材料在盆底组织中的组织相容性差及上市前缺乏适当的监管批准程序等因素引起的。用于疝修补的外科网片已发展了很多年,从金属植入物到编织的聚丙烯网片,这些材料继而被用于POP的治疗。在过去几十年,外科网片已通过不断的改革在疝的治疗上获得较好的效果。因此,可以通过新型材料的开发或组织工程技术得到更适用于治疗POP的新材料。本文旨在探讨聚丙烯网片如何发展为用于修补腹壁疝的材料继而用于治疗POP。此外,我们还探讨了网片特性与不良网片并发症之间的关系。最后,我们还讨论了一些新型网片以及组织工程学在POP治疗中的应用前景。

The use of transvaginal mesh in the treatment of pelvic organ prolapse (POP) has caused much controversy in recent years, providing an effective minimally invasive treatment for the patient with POP, while leading to some serious mesh-related complications. These adverse mesh-related complications were partly caused by poor histocompatibility of mesh materials in pelvic floor tissue, and partly were due to the lack of appropriate regulatory approval procedures before marketing. From the metal implants to the woven polypropylene mesh, the surgical mesh for hernia repair has been developed for many years. These mesh materials are then used in the treatment of POP. In the past few decades, surgical mesh has achieved good results in the treatment of hernia through continuous reform. Therefore, the development of new mesh materials or tissue engineering technology can be more suitable for the treatment of POP. The purpose of this review is to explore how polypropylene mesh can be developed to repair the abdominal hernia and then be used in the treatment of POP. In addition, this text also discussed the relationship between the characteristics of mesh and the bad complications of mesh. Finally, this text also discussed the application prospect of some new mesh and tissue engineering in the treatment of POP.

[1]
Li ZY, Zhu L, Xu T, et al. An epidemiologic study of pelvic organ prolapse in urban Chinese women: a population-based sample in China[J]. Zhonghua Yi Xue Za Zhi, 2019, 99(11): 857-861.
[2]
Brown JS, Waetjen LE, Subak LL, et al. Pelvic organ prolapse surgery in the United States, 1997[J]. Am J Obstet Gynecol, 2002, 186(4): 712-716.
[3]
Ko KJ, Lee KS. Current surgical management of pelvic organ prolapse: Strategies for the improvement of surgical outcomes[J]. Investig Clin Urol, 2019, 60(6): 413-424.
[4]
Bringman S, Conze J, Cuccurullo D, et al. Hernia repair: the search for ideal meshes[J]. Hernia, 2010, 14(1): 81-87.
[5]
Petros PE, Ulmsten UI. An integral theory of female urinary incontinence. Experimental and clinical considerations[J]. Acta Obstet Gynecol Scand Suppl, 1990, 153: 7-31.
[6]
DeLancey JO. Structural support of the urethra as it relates to stress urinary incontinence: the hammock hypothesis[J]. Am J Obstet Gynecol, 1994, 170(6): 1713-1720; discussion 1720-1723.
[7]
Glazener CM, Breeman S, Elders A, et al. Mesh, graft, or standard repair for women having primary transvaginal anterior or posterior compartment prolapse surgery: two parallel-group, multicentre, randomised, controlled trials(PROSPECT)[J]. Lancet(London, England), 2017, 389(10067): 381-392.
[8]
Meyer W. IX. The implantation of silver filigree for the closure of large hernia apertures[J]. Ann Surg, 1902, 36(5): 767-778.
[9]
Flynn WJ, Brant AE, Nelson GG. A four and one-half year analysis of tantalum gauze used in the repair of ventral hernia[J]. Ann Surg, 1951, 134(6): 1027-1034.
[10]
Wolstenholme JT. Use of commercial dacron fabric in the repair of inguinal hernias and abdominal wall defects[J]. AMA Arch Surg, 1956, 73(6): 1004-1008.
[11]
Usher FC. A new plastic prosthesis for repairing tissue defects of the chest and abdominal wall[J]. Am J Surg, 1959, 97(5): 629-633.
[12]
Usher FC, Allen JE, Jr, et al. Polypropylene monofilament. A new, biologically inert suture for closing contaminated wounds[J]. JAMA, 1962, 179: 780-782.
[13]
Smietański M, Bury K, Smietańska IA, et al. Five-year results of a randomised controlled multi-centre study comparing heavy-weight knitted versus low-weight, non-woven polypropylene implants in Lichtenstein hernioplasty[J]. Hernia, 2011, 15(5): 495-501.
[14]
DeBord JR. The historical development of prosthetics in hernia surgery[J]. Surg Clin North Am, 1998, 78(6): 973-1006.
[15]
Ulmsten U, Henriksson L, Johnson P, et al. An ambulatory surgical procedure under local anesthesia for treatment of female urinary incontinence[J]. Int Urogynecol J Pelvic Floor Dysfunct, 1996, 7(2): 81-85; discussion 85-86.
[16]
Wang C, Christie AL, Zimmern PE. Long-term occurrence of secondary compartment pelvic organ prolapse after open mesh sacrocolpopexy for symptomatic prolapse[J]. Neurourol Urodyn, 2018, 37(3): 1101-1105.
[17]
Cundiff GW, Varner E, Visco AG, et al. Risk factors for mesh/suture erosion following sacral colpopexy[J]. Am J Obstet Gynecol, 2008, 199(6): 688. e1-5.
[18]
Nygaard I, Brubaker L, Zyczynski HM, et al. Long-term outcomes following abdominal sacrocolpopexy for pelvic organ prolapse[J]. JAMA, 2013, 309(19): 2016-2024.
[19]
Maher C, Feiner B, Baessler K, et al. Transvaginal mesh or grafts compared with native tissue repair for vaginal prolapse[J]. Cochrane Database Syst Rev, 2016, 2(2): Cd012079.
[20]
Milani AL, Damoiseaux A, IntHout J, et al. Long-term outcome of vaginal mesh or native tissue in recurrent prolapse: a randomized controlled trial[J]. Int Urogynecol J, 2018, 29(6): 847-858.
[21]
Berger RL, Li LT, Hicks SC, et al. Development and validation of a risk-stratification score for surgical site occurrence and surgical site infection after open ventral hernia repair[J]. J Am Coll Surg, 2013, 217(6): 974-982.
[22]
Semmens JP, Wagner G. Estrogen deprivation and vaginal function in postmenopausal women[J]. JAMA, 1982, 248(4): 445-448.
[23]
Roman S, Mangir N, Hympanova L, et al. Use of a simple in vitro fatigue test to assess materials used in the surgical treatment of stress urinary incontinence and pelvic organ prolapse[J]. Neurourol Urodyn, 2019, 38(1): 107-15.
[24]
Klinge U, Klosterhalfen B, Birkenhauer V, et al. Impact of polymer pore size on the interface scar formation in a rat model[J]. J Surg Res, 2002, 103(2): 208-214.
[25]
Brown BN, Mani D, Nolfi AL, et al. Characterization of the host inflammatory response following implantation of prolapse mesh in rhesus macaque[J]. Am J Obstet Gynecol, 2015, 213(5): 668. e1-10.
[26]
Knight KM, Moalli PA, Abramowitch SD. Preventing mesh pore collapse by designing mesh pores with auxetic geometries: a comprehensive evaluation via computational modeling[J]. J Biomech Eng, 2018, 140(5): 0510051-0510058.
[27]
Iakovlev VV, Guelcher SA, Bendavid R. Degradation of polypropylene in vivo: a microscopic analysis of meshes explanted from patients[J]. J Biomed Mater Res B Appl Biomater, 2017, 105(2): 237-248.
[28]
Robichaud A, Bélanger M, Poirier M, et al. Avoidance of the vaginal incision site for mesh placement in vaginal wall prolapse surgery: a prospective study[J]. Eur J Obstet Gynecol Reprod Biol, 2017, 217: 131-136.
[29]
Leanza V, Zanghì G, Vecchio R, et al. How to prevent mesh erosion in transobturator Tension-Free Incontinence Cystocoele Treatment (TICT): a comparative survey[J]. G Chir, 2015; 36(1): 21-25.
[30]
Orenstein SB, Saberski ER, Kreutzer DL, et al. Comparative analysis of histopathologic effects of synthetic meshes based on material, weight, and pore size in mice[J]. J Surg Res, 2012, 176(2): 423-429.
[31]
Feola A, Pal S, Moalli P, et al. Varying degrees of nonlinear mechanical behavior arising from geometric differences of urogynecological meshes[J]. J Biomech, 2014, 47(11): 2584-2589.
[32]
Milani AL, Heidema WM, van der Vloedt WS, et al. Vaginal prolapse repair surgery augmented by ultra lightweight titanium coated polypropylene mesh[J]. Eur J Obstet Gynecol Reprod Biol, 2008, 138(2): 232-238.
[33]
Hung MJ, Wen MC, Huang YT, et al. Fascia tissue engineering with human adipose-derived stem cells in a murine model: implications for pelvic floor reconstruction[J]. J Formos Med Assoc, 2014, 113(10): 704-715.
[34]
Roman S, Mangir N, Bissoli J, et al. Biodegradable scaffolds designed to mimic fascia-like properties for the treatment of pelvic organ prolapse and stress urinary incontinence[J]. J Biomater Appl, 2016, 30(10): 1578-1588.
[35]
Hympánová L, Rynkevic R, Román S, et al. Assessment of electrospun and ultra-lightweight polypropylene meshes in the sheep model for vaginal surgery[J]. Eur Urol Focus, 2020, 6(1): 190-198.
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