切换至 "中华医学电子期刊资源库"

中华疝和腹壁外科杂志(电子版) ›› 2021, Vol. 15 ›› Issue (01) : 35 -39. doi: 10.3877/cma.j.issn.1674-392X.2021.01.009

所属专题: 文献

临床论著

腹腔镜下不同术式和开放手术疝修补术对腹股沟疝治疗效果的前瞻性随机对照研究
吴浩瀚1,(), 吴文涌2, 张顺1, 李立祥1, 徐光武1   
  1. 1. 231500 安徽省合肥市庐江县人民医院普外科
    2. 230022 合肥,安徽医科大学第一附属医院普外科
  • 收稿日期:2020-05-23 出版日期:2021-02-18
  • 通信作者: 吴浩瀚
  • 基金资助:
    安徽医科大学基础与临床合作研究提升计划项目(2019xkjT015)

Efficacy of different laparoscopic procedures and open hernia repair for inguinal hernia: A prospective randomized controlled study

Haohan Wu1,(), Wenyong Wu2, Shun Zhang1, Lixiang Li1, Guangwu Xu1   

  1. 1. Department of General Surgery, Lujiang County People's Hospital, Hefei 231500, China
    2. Department of General Surgery, First affiliated Hospital of Anhui Medical University, Hefei 230022, China
  • Received:2020-05-23 Published:2021-02-18
  • Corresponding author: Haohan Wu
引用本文:

吴浩瀚, 吴文涌, 张顺, 李立祥, 徐光武. 腹腔镜下不同术式和开放手术疝修补术对腹股沟疝治疗效果的前瞻性随机对照研究[J/OL]. 中华疝和腹壁外科杂志(电子版), 2021, 15(01): 35-39.

Haohan Wu, Wenyong Wu, Shun Zhang, Lixiang Li, Guangwu Xu. Efficacy of different laparoscopic procedures and open hernia repair for inguinal hernia: A prospective randomized controlled study[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2021, 15(01): 35-39.

目的

比较腹腔镜经腹腹膜前疝修补术(TAPP)、腹腔镜完全腹膜外疝修补术(TEP)、开放手术疝修补术对腹股沟疝的治疗效果。

方法

分析2018年1月至2020年1月于安徽省合肥市庐江县人民医院普外科行腹股沟疝手术治疗90例患者的资料。依据患者所采用的手术方法不同分为开放手术疝修补术组(A组),TAPP组(B组),TEP组(C组),各30例。对比3组患者的手术时间、失血量、术后12 h视觉模拟评分法(VAS)、术后下床活动时间、医疗费用、术前及术后3 d的血清去甲肾上腺素(NE)、肾上腺素(E)、促肾上腺皮质激素(ACTH)、皮质醇(Cor)、术后并发症及复发情况。

结果

3组患者的手术耗时,差异无统计学意义(P>0.05)。A组患者的失血量、术后12 h VAS评分、术后下床活动时间、总住院时间均高于B组和C组,B组患者的术后12 h VAS评分、术后下床活动时间高于C组,A组的医疗费用最低,B次之,且差异有统计学意义(F=58.395,-0.326,-0.326,-0.326;P<0.05)。3组术前的NE、E、ACTH及Cor差异无统计学意义(均P>0.05)。术后3 d,3组的NE、E、ACTH、Cor较术前均增高;A组术后3 d的NE、E、ACTH、Cor最高,C组最低(F=1.052,12.789,1.077,18.368,1.189,17.115,1.190,20.325;P<0.05)。3组患者的术后各类并发症的结果差异无统计学意义(χ2=3.208,P>0.05)。3组患者在术后3个月内均未出现腹股沟疝复发。

结论

开放手术疝修补术、TAPP、TEP在腹股沟疝的治疗中各具优势,实际临床工作中需要根据患者的实际情况进行选择。

Objective

To explore the difference in the therapeutic effects of laparoscopic preperitoneal hernia repair (TAPP), laparoscopic totally extraperitoneal hernia repair (TEP), and open hernia repair on inguinal hernia.

Methods

A retrospective analysis of the data of 90 patients who underwent inguinal hernia surgery at the General Surgery Department of Lujiang County People's Hospital from January 2017 to July 2019. The patients were grouped according to the different surgical methods: 30 patients with open hernia repair were regarded as group A, 30 patients with TAPP as group B, and 30 patients with TEP as group C. Operation conditions [operation time, blood loss, postoperative 12 hours pain (VAS score), postoperative ambulation time, total hospital stay, medical expenses], stress response indexes [preoperative and postoperative 3 days serum norepinephrine (NE), epinephrine (E), corticotropin (ACTH), cortisol (Cor)], postoperative complications, and recurrence were compared among the 3 groups.

Results

There was no statistically significant difference in operation time among the 3 groups of patients (P>0.05). The blood loss, postoperative VAS score at 12 hours, postoperative ambulation time, and total length of hospital stay in group A were higher than those of groups B and C. The postoperative VAS score at 12 hours and postoperative ambulation time in group B were higher than those of group C. The medical expenses of group A were lowest, followed by group B. The preoperative NE, E, ACTH and Cor data of the three groups were not statistically different (all P>0.05). At 3 days postoperatively, NE, E, ACTH, and Cor in the 3 groups increased; NE, E, ACTH, and Cor in group A were higher than those in group B, and NE, E, ACTH, and Cor in group B were higher than those in group C (all P<0.05). There was no significant difference in the data of various postoperative complications among the three groups (P>0.05). No recurrence within 3 months after surgery occurred.

Conclusion

Open hernia repair, TAPP, and TEP have their own advantages in the treatment of inguinal hernias. In actual clinical work, it is necessary to choose according to the actual situation of the patient.

表1 3组患者一般临床资料对比
表2 3组患者手术情况相关指标(±s
表3 3组术前以及术后3 d应激反应指标(±s
表4 2组术后并发症情况[例(%)]
[1]
马先,贺杰,马俊帅. 丹红注射液结合抗菌药物对腹股沟疝术后血清MMP-2、MMP-9、TIMP-2、TIMP-1及应激指标作用机制研究[J]. 世界中医药, 2019, 14(9): 2404-2407.
[2]
Cihangir A, Fir ATK, Erkinbek O, et al. Outcome of the patients with chronic mesh infection following open inguinal hernia repair[J]. J Korean Surg Soc, 2013, 84(5): 287-291.
[3]
胡昊勰,吴其肯,夏龙飞, 等. 疝环充填式无张力疝修补术治疗成年人腹股沟疝的临床效果观察[J]. 中国基层医药, 2020, 27(19): 2394-2397.
[4]
陆鉴,甘建春,黄鹄, 等. 局麻下腹膜前间隙疝无张力修补术与李金斯坦疝无张力修补术治疗腹股沟疝效果比较[J]. 浙江医学, 2020, 42(11): 1181-1183.
[5]
来源,张锦,李凯. 右美托咪定不同给药方式对老年腹股沟疝无张力修补术患者神经阻滞麻醉效果与安全性的影响[J]. 药物不良反应杂志, 2020, 22(5): 283-288.
[6]
丁继兵,林家国,刘小军. 地塞米松复合罗哌卡因腹横肌平面阻滞对腹腔镜结肠癌术后急性疼痛和炎症因子的影响[J]. 重庆医学, 2020, 49(18): 3087-3090, 3097.
[7]
马颂章. 疝外科学[M]. 5 版. 北京: 人民卫生出版社, 2002: 222.
[8]
中华医学会外科学分会疝与腹壁外科学组,中国医师协会外科医师分会疝和腹壁外科医师委员会. 成人腹股沟疝诊断和治疗指南(2018年版)[J/OL]. 中华疝和腹壁外科杂志(电子版), 2018, 12(4): 244.
[9]
Andresen K, Burcharth J, Fonnes S, et al. Short-term outcome after Onstep versus Lichtenstein technique for inguinal hernia repair: results from a randomized clinical trial[J]. Hernia, 2015, 19(6): 871-877.
[10]
Zwaans WAR, Verhagen T, Roumen RM H, et al. Factors determining outcome after surgery for chronic groin pain following a Lichtenstein hernia repair[J]. World J Surg, 2015, 39(11): 2652-2662.
[11]
王领. 成人腹股沟疝患者行前入路腹膜间隙无张力疝修补术的疗效分析[J]. 陕西医学杂志, 2017, 46(4): 515-516.
[12]
彭友,杨洪雷. 腹腔镜与开放式无张力疝修补术治疗成人腹股沟疝效果观察[J]. 检验医学与临床, 2017, 14(z2): 151-153.
[13]
徐时,高海德,俞晓峰. 不同手术方式治疗腹股沟疝的疗效差异[J]. 中国中西医结合外科杂志, 2017, 23(4): 410-412.
[14]
曾国祥,黄文伟,黄修仿. TAPP与Lichtenstein术治疗成人腹股沟复发疝的疗效对比[J/OL]. 中华疝和腹壁外科杂志(电子版), 2017, 11(5): 387-389.
[15]
张岳农,肖丹,林伟雄, 等. 视频喉镜、直接喉镜和光导纤维支气管镜经鼻气管插管对血流动力学和炎症应激反应的比较[J]. 中国内镜杂志, 2016, 22(7): 51-56.
[1] 燕速, 霍博文. 腹腔镜食管胃结合部腺癌根治性切除术[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 13-13.
[2] 母德安, 李凯, 张志远, 张伟. 超微创器械辅助单孔腹腔镜下脾部分切除术[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 14-14.
[3] 李国新, 陈新华. 全腹腔镜下全胃切除术食管空肠吻合的临床研究进展[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 1-4.
[4] 李子禹, 卢信星, 李双喜, 陕飞. 食管胃结合部腺癌腹腔镜手术重建方式的选择[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 5-8.
[5] 李乐平, 张荣华, 商亮. 腹腔镜食管胃结合部腺癌根治淋巴结清扫策略[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 9-12.
[6] 陈方鹏, 杨大伟, 金从稳. 腹腔镜近端胃癌切除术联合改良食管胃吻合术重建His角对术后反流性食管炎的效果研究[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 15-18.
[7] 许杰, 李亚俊, 韩军伟. 两种入路下腹腔镜根治性全胃切除术治疗超重胃癌的效果比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 19-22.
[8] 李刘庆, 陈小翔, 吕成余. 全腹腔镜与腹腔镜辅助远端胃癌根治术治疗进展期胃癌的近中期随访比较[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 23-26.
[9] 任佳, 马胜辉, 王馨, 石秀霞, 蔡淑云. 腹腔镜全胃切除、间置空肠代胃术的临床观察[J/OL]. 中华普外科手术学杂志(电子版), 2025, 19(01): 31-34.
[10] 王庆亮, 党兮, 师凯, 刘波. 腹腔镜联合胆道子镜经胆囊管胆总管探查取石术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 313-313.
[11] 杨建辉, 段文斌, 马忠志, 卿宇豪. 腹腔镜下脾部分切除术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 314-314.
[12] 叶劲松, 刘驳强, 柳胜君, 吴浩然. 腹腔镜肝Ⅶ+Ⅷ段背侧段切除[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(02): 315-315.
[13] 郭兵, 王万里, 何凯, 黄汉生. 腹腔镜下肝门部胆管癌根治术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 143-143.
[14] 李凯, 陈淋, 苏怀东, 向涵, 张伟. 超微创器械在改良单孔腹腔镜巨大肝囊肿开窗引流及胆囊切除中的应用[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 144-144.
[15] 魏丽霞, 张安澜, 周宝勇, 李明. 腹腔镜下Ⅲb型肝门部胆管癌根治术[J/OL]. 中华肝脏外科手术学电子杂志, 2025, 14(01): 145-145.
阅读次数
全文


摘要