切换至 "中华医学电子期刊资源库"

中华疝和腹壁外科杂志(电子版) ›› 2019, Vol. 13 ›› Issue (02) : 162 -165. doi: 10.3877/cma.j.issn.1674-392X.2019.02.016

所属专题: 文献

论著

疝补片修补及开腹减压术在腹腔间室综合征伴腹腔感染治疗中的应用
王乃金1, 闫波2,(), 应浩杰1, 史进1, 马军伟1, 苏珂1   
  1. 1. 255300 山东,解放军第九六〇医院淄博院区普外科
    2. 255300 山东,解放军第九六〇医院重症医学
  • 收稿日期:2018-12-29 出版日期:2019-04-18
  • 通信作者: 闫波

Application of herniorrhaphy and open decompression in the treatment of ACS with abdominal infection

Naijin Wang1, Bo Yan2,,(), Haojie Ying1, Jin Shi1, Junwei Ma1, Ke Su1   

  1. 1. Department of General Surgery, Zibo Hospital District, 960 Hospital of PLA, Shandong Zibo 255300, China
    2. Department of Critical Care Medicine, Zibo Hospital District, 960 Hospital of PLA, Shandong Zibo 255300, China
  • Received:2018-12-29 Published:2019-04-18
  • Corresponding author: Bo Yan
  • About author:
    Corresponding author: Yan Bo, Email:
引用本文:

王乃金, 闫波, 应浩杰, 史进, 马军伟, 苏珂. 疝补片修补及开腹减压术在腹腔间室综合征伴腹腔感染治疗中的应用[J]. 中华疝和腹壁外科杂志(电子版), 2019, 13(02): 162-165.

Naijin Wang, Bo Yan, Haojie Ying, Jin Shi, Junwei Ma, Ke Su. Application of herniorrhaphy and open decompression in the treatment of ACS with abdominal infection[J]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2019, 13(02): 162-165.

目的

探讨疝补片修补及开腹减压术对腹腔间室综合征(abdominal compartment syndrome,ACS)伴腹腔感染患者的临床疗效,分析其应用价值。

方法

回顾性分析2011年4月至2018年4月,解放军第九六〇医院淄博院区收治的ACS伴腹腔感染42例患者的临床资料,根据患者及家属意愿分为2组。试验组患者18例,采用疝补片修补术;对照组患者24例,采用开腹减压修补术。比较2组患者治疗后的总有效率,治疗前后的急性生理与慢性健康状况(acute physiology and chronic health evaluation,APACHE)Ⅱ评分,并对比分析治疗前后患者的血清炎性因子C反应蛋白(C-reactive protein,CRP)、白细胞介素6(interleukin-6,IL-6)和肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)水平。

结果

2组患者治疗病情好转,试验组总有效率(83.33%)高于对照组患者(79.17%),但差异无统计学意义(P=0.773);2组患者治疗后APACHEⅡ评分均下降,但试验组患者下降程度大于对照组,差异有统计学意义(P<0.01);治疗后,患者炎症反应明显减轻,CRP、IL-6、TNF-α均下降,治疗前后差异均有统计学意义(P<0.01),且试验组患者炎症缓解程度显著大于对照组,差异有统计学意义(P<0.01)。

结论

疝补片修补应用于临床治疗ACS伴腹腔感染能有效改善患者血清炎性因子水平,缓解患者临床症状,有效改善患者健康状况,降低患者腹内压,为临床治疗提供新选择。

Objective

To explore the clinical efficacy of herniorrhaphy and open decompression in the treatment of (ACS) with abdominal infection in patients with celiac compartment syndrome, and to analyze its application value.

Methods

From April 2011 to April 2018, 44 cases of ACS with abdominal infection were analyzed retrospectively. Among them, 18 cases were treated with herniorrhaphy and 24 cases were treated with open decompression. The clinical data of patients before and after treatment were collected, the therapeutic effects of patients after treatment were compared, the APACHEⅡ scores of patients before and after treatment were compared, and the changes of serum inflammatory factors CRP, IL-6 and TNF-α before and after treatment were compared.

Results

The two groups of patients improved their treatment and had certain curative effect. The total effective rate of the experimental group (83.33%) was higher than that of the control group (79.17%), but there was no significant difference (P=0.773). The APACHEⅡ scores of the two groups were decreased after treatment. The degree of decline was greater than that of the control group (P<0.01). After treatment, the inflammatory response was significantly relieved, and the inflammatory markers CRP, IL-6, and TNF-α were decreased. There were statistical differences before and after treatment, and the degree of inflammation was significantly reduced in the experimental group. Greater than the control group (P<0.01).

Conclusion

Herniorrhaphy for clinical treatment of ACS with abdominal infection can effectively improve serum inflammatory factor levels, alleviate clinical symptoms, improve patient health, reduce intra-abdominal pressure, and provide new options for clinical treatment.

表1 2组患者总有效率比较
表2 APACHEⅡ评分和血清炎性因子变化比较
[1]
孙传涛,李胜保,童强, 等. 早期内镜治疗重症急性胰腺炎并发腹腔内高压/腹腔间隔室综合征的效果研究[J]. 中国内镜杂志, 2018, 24(2): 63-67.
[2]
田湘萍,刘兰霞,许建民, 等. 早期血液滤过对重症急性胰腺炎合并腹腔间隔室综合征的影响[J]. 中国现代医学杂志, 2017, 27(23): 100-105.
[3]
王峰,曾玉剑,刘佳, 等. 转化生长因子-β通路在腹腔间隔室综合征大鼠模型肠黏膜损伤修复中的作用[J]. 广东医学, 2017, 38(24): 3772-3775.
[4]
黄洋峰,蒋薇,曾杰. C反应蛋白与血清乳酸判断老年患者危重急腹症感染预后的临床意义[J]. 重庆医学, 2015, 44(18): 2485-2487.
[5]
许威,于建平,韩晓鹏, 等. 腹腔开放疗法治疗腹腔重度感染合并腹腔室隔综合征的临床应用[J]. 中华临床感染病杂志, 2015, 8(003): 272-273.
[6]
杨杰,尚现章,梁国兴, 等. 腹腔双套管持续冲洗负压引流治疗腹腔严重感染的效果[J]. 武警医学, 2018, 29(05): 453-455.
[7]
戎世捧,姚胜,张妍, 等. 负压封闭引流技术治疗腹壁切口感染的效果[J/CD]. 中华卫生应急电子杂志, 2015, 1(3): 218-219.
[8]
赵丽君,吴金玲,苏琳, 等. 腹腔开放疗法治疗严重腹腔感染患者的护理[J]. 华南国防医学杂志, 2017, 31(9): 638-639.
[9]
尹兆强,冯雪亮,苑昭奖, 等. 严重腹腔感染患者血清炎性指标表达水平与病情严重程度的相关性分析[J]. 疑难病杂志, 2018, 17(6): 576-579.
[10]
罗旭娟,彭燕,石蕾, 等. 精制芒硝与柴芍承气汤辅助治疗重度急性胰腺炎并腹腔间隔室综合征[J]. 实用医学杂志, 2018, 34(8): 162-165.
[11]
樊俊斌,蔺岗,刘文学. 负压封闭引流敷料在腹腔间隔室综合征腹壁缺损中的应用[J]. 中国药物与临床, 2017, 17(6): 884-886.
[12]
符宜龙,舒艾娅,罗艳, 等. 限制性液体复苏联合连续性肾脏替代治疗在重症急性胰腺炎并发腹腔间隔室综合征治疗中的应用价值[J]. 中华消化外科杂志, 2017, 16(10): 1042-1047.
[1] 高文伯, 李明, 张运昊. 进展期肺癌炎症指数对三阴性乳腺癌的预后价值和临床意义[J]. 中华乳腺病杂志(电子版), 2023, 17(04): 210-217.
[2] 刘英, 李群, 常文静, 郑云辉, 臧学峰. 老年重症感染性休克患者病原菌分布特点及心功能、炎性因子指标变化的临床分析[J]. 中华损伤与修复杂志(电子版), 2021, 16(01): 59-63.
[3] 李存权, 崔磊, 柳科军, 李政权, 刘俊豪, 卜阳. 胰十二指肠切除术后复杂腹腔感染的危险因素分析及病原菌构成[J]. 中华普通外科学文献(电子版), 2022, 16(06): 417-421.
[4] 张娟, 马静, 杨雷, 刘牧林, 徐鑫星, 叶枫林. FTS对腹腔镜结直肠癌患者术后并发症和炎性因子的影响[J]. 中华普外科手术学杂志(电子版), 2022, 16(02): 218-221.
[5] 钱晓英, 吴新, 徐婷婷. 颅脑损伤并发呼吸衰竭患者早期机械通气的效果分析[J]. 中华肺部疾病杂志(电子版), 2023, 16(04): 526-528.
[6] 王小蓓, 秦雯, 符天选, 谭春苗. AECOPD睡眠障碍对肺功能炎性因子及焦虑抑郁状态的影响[J]. 中华肺部疾病杂志(电子版), 2023, 16(02): 260-262.
[7] 孔菲, 王研, 吴昱华. 比阿培南联合莫西沙星对重症肺炎患者疗效、炎性因子及血清CD40L、VACM-1的影响[J]. 中华肺部疾病杂志(电子版), 2022, 15(04): 533-535.
[8] 陈若红, 冯业成, 严灵丽. 热毒宁联合阿奇霉素序贯疗法对支原体肺炎患儿的影响[J]. 中华肺部疾病杂志(电子版), 2022, 15(01): 88-90.
[9] 罗妍妍, 陈青. 益生菌辅治小儿哮喘及对S100β蛋白、TLR4与炎性免疫因子的影响[J]. 中华肺部疾病杂志(电子版), 2021, 14(05): 608-610.
[10] 符晶, 陈兴峰, 王秀川. 呼吸康复训练对慢性阻塞性肺疾病患者的影响[J]. 中华肺部疾病杂志(电子版), 2021, 14(02): 208-211.
[11] 胡飞龙, 路璐. 胞磷胆碱对大脑中动脉缺血性脑卒中恢复期的疗效[J]. 中华脑科疾病与康复杂志(电子版), 2023, 13(01): 51-56.
[12] 高西杰, 李新民, 唐水英, 郝柯楠, 吴德堤, 田晨, 何晓峰. 介入置管行臭氧水冲洗治疗胸腹腔感染合并外瘘的临床观察[J]. 中华介入放射学电子杂志, 2021, 09(04): 395-399.
[13] 张晓梅, 陈美玲. 岩盐气溶胶治疗老年尘肺患者疗效分析[J]. 中华老年病研究电子杂志, 2021, 08(02): 26-29.
[14] 阿孜古丽·阿力木江, 买买提·依斯热依力, 王婧, 王永康, 陆萍, 克力木·阿不都热依木. 心理应激对雌性小鼠胃黏膜炎症和卵巢功能早衰的影响[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 69-76.
[15] 赵长伟, 买买提·依斯热依力, 迪丽达尔·阿迪里, 王永康, 克力木·阿不都热依木. 莫沙必利对心理应激诱导小鼠食管炎症发生的影响及作用[J]. 中华胃食管反流病电子杂志, 2022, 09(03): 156-160.
阅读次数
全文


摘要