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中华疝和腹壁外科杂志(电子版) ›› 2018, Vol. 12 ›› Issue (03) : 199 -203. doi: 10.3877/cma.j.issn.1674-392X.2018.03.010

所属专题: 文献

论著

猪小肠黏膜下层脱细胞基质补片与轻量聚丙烯补片在腹股沟疝Lichtenstein修补术中的对比研究
戴伟钢1, 左继东1, 谭进富1, 袁玉杰1, 袁凯涛1, 冯伟东1, 赵琼云1, 谭敏1,()   
  1. 1. 510080 广州,中山大学附属第一医院胃肠外科中心,疝与腹壁外科
  • 收稿日期:2017-12-06 出版日期:2018-06-18
  • 通信作者: 谭敏
  • 基金资助:
    广东省公益研究和能力建设专项资金资助项目(2016A010103038); 国家自然科学基金-青年基金资助项目(81602660,81401307)

Safety and efficacy of porcine small intestine submucosa mesh versus lightweight polypropylene mesh for Lichtenstein inguinal hernia repair

Weigang Dai1, Jidong Zuo1, Jinfu Tan1, Yujie Yuan1, Kaitao Yuan1, Weidong Feng1, Qiongyun Zhao1, Min Tan1,()   

  1. 1. Department of Gastrointestinal Surgery, Hernia and Abdominal Wall Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China
  • Received:2017-12-06 Published:2018-06-18
  • Corresponding author: Min Tan
  • About author:
    Corresponding author: Tan Min, Email:
引用本文:

戴伟钢, 左继东, 谭进富, 袁玉杰, 袁凯涛, 冯伟东, 赵琼云, 谭敏. 猪小肠黏膜下层脱细胞基质补片与轻量聚丙烯补片在腹股沟疝Lichtenstein修补术中的对比研究[J/OL]. 中华疝和腹壁外科杂志(电子版), 2018, 12(03): 199-203.

Weigang Dai, Jidong Zuo, Jinfu Tan, Yujie Yuan, Kaitao Yuan, Weidong Feng, Qiongyun Zhao, Min Tan. Safety and efficacy of porcine small intestine submucosa mesh versus lightweight polypropylene mesh for Lichtenstein inguinal hernia repair[J/OL]. Chinese Journal of Hernia and Abdominal Wall Surgery(Electronic Edition), 2018, 12(03): 199-203.

目的

探讨猪小肠黏膜下层脱细胞基质(porcine small intestine submucosa,SIS)补片对比轻量聚丙烯(polypropylene mesh,PP)补片在腹股沟疝Lichtenstein修补术中应用的安全性和短期疗效。

方法

回顾性分析2012年1月至2015年8月,中山大学附属第一医院使用SIS补片和轻量PP补片做单侧腹股沟疝Lichtenstein修补术的连续男性病例资料,SIS组和PP组分别纳入64例,比较2组患者手术安全性和短期疗效。

结果

SIS组与PP组在术后24 h疼痛评分、发热、伤口脂肪液化、血清肿、尿潴留、睾丸并发症发生率比较,差异无统计学意义(P均>0.05)。2组均无手术部位感染和血肿发生病例。2组均无复发病例。SIS组在术后慢性疼痛(14.1%比15.6%,χ2=0.062,P=0.804),术后腹股沟区不适感(12.5%比17.2%,χ2=0.556,P=0.456),异物感(3.1%比4.7%,P=1.000)均低于PP组,但2组差异无统计学意义(P均>0.05)。2组在术后均无明显射精疼痛或障碍,无睾丸萎缩。PP组有2例(3.1%)患者出现手术侧睾丸肿大。

结论

SIS补片对比轻量PP补片在腹股沟疝Lichtenstein修补术中应用的安全性和短期疗效是相当的,其长期疗效仍有待进一步观察。

Objective

The purpose of this study was to investigate the safety and efficacy of porcine small intestine submucosa (SIS) mesh versus Lightweight polypropylene (PP) mesh in Lichtenstein repair of inguinal hernia.

Methods

From January 1 2012 to August 31 2015, the consecutive male patients of unilateral inguinal hernia undergoing Lichtenstein repair using SIS mesh and lightweight PP mesh in the First Affiliated Hospital of Sun Yat-Sen University were analyzed retrospectively. SIS group and PP group were enrolled in 64 patients respectively. The safety and short-term efficacy of the two groups were compared.

Results

There were no significant differences in pain score at 24 hours after operation, fever, wound fat liquefaction, serum swelling, urinary retention, testicular complications between the SIS group and the PP group (all P>0.05). There were no surgical site infection and hematoma cases in two groups. No recurrence occurred in two groups. Although the severity of postoperative chronic pain (14.1% vs 15.6%, χ2=0.062, P=0.804), postoperative groin discomfort (12.5% vs 17.2%, χ2=0.556, P=0.456), foreign body sensation (3.1% vs 4.7%, P=1.000) in the SIS group were lower than those in the PP group, but there was no statistically significant difference between the two groups (all P >0.05). There were no obvious ejaculatory pain or obstruction and testicular atrophy occurred in two groups. There were two cases (3.1%) of testicular swelling in PP group.

Conclusions

The safety and short-term efficacy of SIS mesh compared with light PP mesh in Lichtenstein repair of inguinal hernia are comparable, but the long-term efficacy remains to be further observed.

表1 2组基线资料比较
表2 2组术后短期疗效比较[例(%)]
表3 2组术后长期疗效比较[例(%)]
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